有哪些信誉好的足球投注网站genetic characterization of human t-cell lymphotropic virus type 1 in mozambique transcontinental lineages drive the htlv-1 endemic人类t细胞淋巴细胞病毒1型的遗传特性在莫桑比克横贯大陆的血统htlv 1流行.pdfVIP
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genetic characterization of human t-cell lymphotropic virus type 1 in mozambique transcontinental lineages drive the htlv-1 endemic人类t细胞淋巴细胞病毒1型的遗传特性在莫桑比克横贯大陆的血统htlv 1流行
Genetic Characterization of Human T-Cell Lymphotropic Virus Type 1 in Mozambique: Transcontinental Lineages Drive the HTLV-1 Endemic 1 2 ˜ 1 1 2 Ana Carolina P. Vicente , Eduardo Samo Gudo , Alena Mayo Iniguez *, Koko Otsuki , Nilesh Bhatt , 3 2 2 3 ´ 3 2 Celina M. Abreu , Adolfo Vubil , Dulce Bila , Orlando C. Ferreira Jr , Amılcar Tanuri , Ilesh V. Jani for the HTLV in Mozambique Study Group ˜ ´ 1 Instituto Oswaldo Cruz, Fundac¸ao Oswaldo Cruz (FIOCRUZ), Rio de Janeiro, Brazil, 2 Departamento de Imunologia, Instituto Nacional de Saude, Maputo, Mozambique, ´ 3 Departamento de Genetica, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil Abstract Background: Human T-Cell Lymphotropic Virus Type 1 (HTLV-1) is the etiological agent of adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). It has been estimated that 10–20 million people are infected worldwide, but no successful treatment is available. Recently, the epidemiology of this virus was addressed in blood donors from Maputo, showing rates from 0.9 to 1.2%. However, the origin and impact of HTLV endemic in this population is unknown. Objective: To assess the HTLV-1 molecular epidemiology in Mozambique and to investigate their relationship with HTLV-1 lineages circulating wo
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