genetic characterization of venezuelan equine encephalitis virus from bolivia, ecuador and peru identification of a new subtype id lineage委内瑞拉马脑炎病毒的遗传特性从玻利维亚、厄瓜多尔和秘鲁的识别新的亚型id血统.pdfVIP

Genetic Characterization of Venezuelan Equine Encephalitis Virus from Bolivia, Ecuador and Peru: Identification of a New Subtype ID Lineage 1 2 ´ 3 4 5 6 Patricia V. Aguilar , A. Paige Adams , Victor Suarez , Luis Beingolea , Jorge Vargas , Stephen Manock , 7 7 1 8 2 5 Juan Freire , Willan R. Espinoza , Vidal Felices , Ana Diaz , Xiaodong Liang , Yelin Roca , Scott C. 2 1 Weaver , Tadeusz J. Kochel * 1 Naval Medical Research Center Detachment, Lima, Peru, 2 Department of Pathology and Center for Tropical Diseases, University of Texas Medical Branch, Galveston, Texas, United States of America, 3 National Institute of Health, Lima, Peru, 4 Office of Epidemiology, Lima, Peru, 5 Centro de Enfermedades Tropicales, Santa Cruz, Bolivia, ´ 6 Hospital Vozandes del Oriente, Shell, Ecuador, 7 Hospital de la IV Division de Amazonas, Puyo, Ecuador, 8 Facultad de Ciencias, Universidad Nacional Agraria La Molina, Lima, Peru Abstract Venezuelan equine encephalitis virus (VEEV) has been responsible for hundreds of thousands of human and equine cases of severe disease in the Americas. A passive surveillance study was conducted in Peru, Bolivia and Ecuador to determine the arboviral etiology of febrile illness. Patients with suspected viral-associated, acute, undifferentiated febrile illness of ,7 days duration were enrolled in the study and blood samples were obtained from each patient and assayed by virus isolation. Demographic and clinical information from each patient was also obtained at the time of voluntary enrollment. In 2005–