荧光纳米材料在食源性致病菌检测中的应用研究进展 - 食品安全质量 .docVIP

荧光纳米材料在食源性致病菌检测中的应用研究进展 刘慧玲1, 2*, 张 恒1, 2, 黄李华1, 2, 吕敬章1, 2, 黄欣迪1, 2 (1. 深圳市检验检疫科学研究院, 深圳 518010; 2. 深圳出入境检验检疫局, 深圳市食品安全检测技术研发重点实验室, 深圳 518045) 摘 要: 食源性致病菌与人类健康密切相关, 食源性疾病爆发造成的社会经济损失不可估量。荧光纳米材料具有小尺寸效应、独特的荧光性能以及可以与各种类型检测方法相结合对食源性致病菌进行检测的特性, 使得其在近几年来发展迅速。可用于食品安全领域的荧光纳米材料主要有量子点(quantum dots)、复合荧光二氧化硅纳米颗粒(the compact fluorescent silica nanoparticles)、金纳米簇(gold nanoclusters)和碳量子点(carbon quantum dots)4种。本文主要综述了这4种不同荧光纳米材料的特点及优势、荧光颗粒制备方法及在食源性致病菌检测领域的应用。 关键词 Research progress on application of fluorescence nanomaterials in detection of foodborne pathogens LIU Hui-Ling1, 2*, ZHANG Heng1, 2, HUANG Li-Hua1, 2, LV Jing-Zhang1, 2, HUANG Xin-Di1, 2 (1. Shenzhen Academy of Inspection and Quarantine, Shenzhen 518010, China; 2. Shenzhen Key Research Laboratory of Detection Technology RD on Food Safety, Shenzhen Entry-Exit and Inspectionand Quarantine Bureau, Shenzhen 518045, China) ABSTRACT: Foodborne pathogenic bacteria are closely related to human health. Social and economic losses caused by foodborne disease outbreak are immeasurable. Fluorescent nanomaterials have characteristics such as small size effect, unique fluorescent properties and the ability to combine with various kinds of detection methods for detecting foodborne pathogens, which make fluorescent nanomaterials develop rapidly in recent years. Fluorescent nanomaterials which can be used in the field of food safety mainly include quantum dots, the compact fluorescent silica nanoparticles, gold nanoparticle cluster and carbon quantum dots. This review summarized the characteristics and advantages of 4 kinds of fluorescence nanomaterials, preparation methods of fluorescent particles and their applications in the detection of foodborne pathogenic bacteria. KEY WORDS: fluorescence nanomaterials; quantum dots; the compact fluorescent silica nanoparticles; gold nanoclusters; carbon quantum dots 1 引言 食源性致病菌是危害人类身体健康、引起食源性疾病爆发的重要致病因子, 食源性致病菌污染造成的食品安全问题, 对我国乃至世界经济造成巨大的损失。在我国, 目前已知常见的食源性致病菌有沙门氏菌、单增李斯特菌、大肠杆菌O157:H7和金黄色葡萄