超滤系统的基本组成和操作.ppt

Basic Components Operation of TFF Systems超滤系统的基本组成和操作 TFF Overview超滤回顾 Components Controls组成控制 Equations and Definitions公式和定义 Step by Step Operation of the process 过程操作的步骤 Basic TFF System Hardware基本超滤系统的硬件 Minimum Requirements:最基本的配置要求: Pumps泵 Holder, Filter module, Piping and Tubing 夹具,过滤膜,管路管件 Tank with Mixerd带搅拌的罐 Retentate Valve(usually a sanitary diaphragm valve)回流阀(通常是卫生级的隔膜阀) Important Additions for proper operation:正确操作的重要条件 Pressure Gauges/Indicators - feed, retentate, permeate压力表/指示器-进口,回流,透出 Flow Meters - retentate and permeate流量计-回流和透出 Extra Valves for cleaning and controlling flow清洗和控制流速的额外阀门 Thermometer温度计 pH, Conductivity, UV Meters PH,电导率,紫外计 Heat Exchanger for cooling or heating 用于冷却或加热的热交换器 Basic TFF System Layout超滤系统示意图 Basic TFF System Layout超滤系统示意图 Basic TFF System Layout超滤系统的示意图 Basic TFF System Layout超滤系统示意图 Basic TFF System Layout超滤系统示意图 Basic TFF System Layout超滤系统示意图 TFF Definitions Equations超滤的定义和公式 Concentration Factor 浓缩因子 CF = Original Volume初始体积 (Vo) Retentate Volume截留体积 (Vr) It also equals...也等于 = Retentate Concentration截留浓度 (Cr) Original Concentration 初始浓度(Co) Also known as…也被认为是… Volume Concentration Factor or Ratio (CF or VCR) 体积浓缩因子或比率 TFF Definitions Equations超滤的定义公式 Mass Balance 物料平衡 Feed Volume = Retentate Volume + Permeate Volume 进液体积 = 回流体积 + 透出体积 Vo = Vr + Vp Feed Flow rate = Retentate Flow Rate + Permeate Flow Rate 进液流速 = 回流流速 + 透出液流速 Qp = Qr + Qp (Vo)(Initial Conc.) = (Vr)(Retentate Conc.)+(Vp)(Permeate Conc.) Vo x Co = (Vr x Cr) + (Vp x Cp) TFF Definitions Equations超滤的定义公式 Yield回收率 Y = V x C Vo x Co Passage透过率 P = Cp Cr Rejection截留率 R = 1 - Cp Cr TFF Parameter Relationships超滤的相关参数 Viscosity粘度 Flow rate x Viscosity = Constant 流速*粘度=常数 Q1 x u1 = Q2 x u2 Q2 = Q1 x u1 u2 Pressure压力 Permeate flow is directly proportional to pressure 透出液流速与压力是成正比的 Double the applied pressure, the permeate