Is ultraviolet B irradiance inversely associated with incidence rates of endometrial cancer an ecological study of 107 countries》.pdfVIP
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Is ultraviolet B irradiance inversely associated with incidence rates of endometrial cancer an ecological study of 107 countries》.pdf
Available online at Preventive Medicine 45 (2007) 327 – 331 /locate/ypmed Is ultraviolet B irradiance inversely associated with incidence rates of endometrial cancer: an ecological study of 107 countries Sharif B. Mohr a , Cedric F. Garland a,⁎, Edward D. Gorham a,b , William B. Grant c , Frank C. Garland a,b a Department of Family and Preventive Medicine 0631C, University of California San Diego, La Jolla CA, USA b Naval Health Research Center, San Diego CA, USA c Sunlight, Nutrition, and Health Research Center, San Francisco CA, USA Available online 4 February 2007 Abstract Objective. The purpose of this study was to perform an ecological analysis of the relationship between low levels of ultraviolet B (UVB) irradiance and age-standardized incidence rates of endometrial cancer by country, controlling for known confounders. Methods. The contributions of UVB irradiance, cloud cover, intake of energy from animal sources, proportion of population overweight, skin pigmentation, per capita cigarette consumption, per capita health expenditure, and total fertility rates, to age-standardized incidence rates of endometrial cancer in 107 countries were assessed using multiple regression. Results. Incidence rates were higher at higher latitudes (R2 =0.47, p 0.01). According to multiple regression, UVB irradiance adjusted for cloud cover was negatively associated with incidence rates (p =0.02), while p
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