补肾固精方治疗阴阳两虚型早期糖尿病肾病临床研究.pdfVIP

2015 年1月第 22卷第1期 中国中医药信息杂志 ·33· 补肾固精方治疗阴阳两虚型早期糖尿病肾病临床研究 闫顺新,郭小舟,张玉军,王金玲 延庆县中医医院,北京 102100 摘要：目的 观察补肾固精方治疗早期糖尿病肾病的临床疗效。方法 将 60 例阴阳两虚型早期糖尿病肾 病患者随机分为治疗组和对照组,治疗组予补肾固精方口服结合西医常规治疗,对照组予西医常规治疗,疗程 3 个月。比较 2 组患者治疗前后临床疗效、中医症状积分、尿白蛋白排泄率(UAER)。结果 治疗组治疗后中医证 候积分低于对照组,差异有统计学意义 (P ＜0.05)。临床疗效总有效率治疗组为 81.48%(22/27),对照组为 64.00%(16/25),治疗组优于对照组(P ＜0.05)。2 组 UAER 比较,差异有统计学意义(P ＜0.05)。结论 在西医 常规治疗基础上加服补肾固精方能改善患者临床症状,减轻肾脏损害程度,对早期糖尿病肾病有较好疗效。 关键词：糖尿病肾病；补肾固精方；中西医结合疗法 DOI：10.3969/j.issn.1005-5304.2015.01.010 中图分类号：R259.872 文献标识码：A 文章编号：1005-5304(2015)01-0033-03 A Clinical Study on Bushen Gujing Recipe in Treating Early Diabetic Nephropathy with Yin-Yang Deficiency Syndrome YAN Shun-xin, GUO Xiao-zhou, ZHANG Yu-jun, WANG Jin-ling (Yanqing County Hospital of Traditional Chinese Medicine, Beijing 102100, China) Abstract ：Objective To investigate the effects of Bushen Gujing Recipe in treating early diabetic nephropathy (DN). Methods Sixty patients of early DN with Yin-Yang deficiency syndrome were randomly divided into treatment group and control group, 30 cases in each group. The control group was treated with conventional western medicine treatment, and the treatment group was treated with Bushen Gujing Recipe combined with the conventional therapy. The treatment course was three months. The clinical efficacy, integral of TCM syndrome, and urinary albumin excretion rate (UAER) of the two groups were compared. Results After the treatment, the integral of TCM symdrome of the treatment group was lower than control group, showed a statistically significant difference (P ＜0.05). The total effective rates of clinical efficacy were 81.48% (22/27) in treatment group, and 64.00% (16/25) in control group. The therapeutic effect of treatment group was better than control group