体重指数对轻度持续性哮喘儿童吸入布地奈德的疗效影响（职称论文资料）.docVIP

体重指数对轻度持续性哮喘儿童吸入布地奈德的疗效影响（职称论文资料） 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：体重指数对轻度持续性哮喘儿童吸入布地奈德的疗效影响 1 1 资料与方法 3 2 结果 4 3 讨论 4 文2：吸入布地奈德对哮喘性支气管炎患儿预后的临床观察 5 1 对象和方法 5 2 结果 6 第二年末哮喘发生率 7 3～4岁身高增长值比较 7 6岁时测呼气峰流速（PEF）比较 7 3 讨论 7 参考文摘引言： 9 原创性声明（模板） 10 文章致谢（模板） 10 正文 体重指数对轻度持续性哮喘儿童吸入布地奈德的疗效影响（职称论文资料） 文1：体重指数对轻度持续性哮喘儿童吸入布地奈德的疗效影响 Efficacy of body mass index on inhaled budesonide for treatment of children with mild peistent asthma YAN Minliang Department of Pediatrics， Zhuzhou Fit Hospital， Hunan Province， Zhuzhou 412000， China [Abstract] Objective: To further explore the effects of body mass index on inhaled budesonide for the treatment of children with mild peistent asthma. Methods: 66 children with mild peistent asthma admitted and treated in the department of pediatrics of our hospital from January 2009 to January 2011 were randomly divided into three groups， namely a group of normal children， a group of overweight children and a group of obese children. All the children were given budesonide inhalation therapy and then the differences of lung function forced expiratory volume in 1 second (FEV1) between the three groups of children were observed. Results: The FEV1 indicato of the three groups of children before and after treatment showed statistical differences (P). FEV1 increased significantly after treatment compared with those before treatment. The FEV1 increase of the group of obese children was statistically different from that of the group of normal children (P)， with the former increase lower than the latter one. Conclusion: Obesity may affect the treatment efficacy of budesonide. [Key words] Mild peistent asthma; Budesonide; Inhalation therapy; Body mass index 哮喘是支气管哮喘的简称，为一种较为常见的慢性呼吸道疾病之一，近年来，哮喘的发病率呈现逐年上升的趋势。哮喘是由多种细胞包括气道的炎性细胞和结构细胞和细胞组分发生变性形成的气道慢性炎症性疾病[1]。临床中以反复发作、气急、胸闷、咳嗽为主要的症状[2]。长期以来，哮喘研究学者们一直在研究肥胖和哮喘之间的关联，有研究表明儿童超重和肥胖都能导致儿童哮喘发生的危险程度，使疾病加重，并且疾病的发生率也随着体重指数的增加而增加。本文笔者通过对本院哮喘患儿的临床研究，分析体重指数对轻度持续性哮喘吸入布地奈德治疗效果的影响，现将报道如下： 1