hladp dq基因多态性与福建汉族人群乙型肝炎病毒感染及其不同结局的关联-association of hl adp dq gene polymorphism with hepatitis b virus infection and its different outcomes in fujian han population.docx

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hladp dq基因多态性与福建汉族人群乙型肝炎病毒感染及其不同结局的关联-association of hl adp dq gene polymorphism with hepatitis b virus infection and its different outcomes in fujian han population.docx

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hladp dq基因多态性与福建汉族人群乙型肝炎病毒感染及其不同结局的关联-association of hl adp dq gene polymorphism with hepatitis b virus infection and its different outcomes in fujian han population

目录英汉缩略名词对照表···········································································3研究背景·····························································································4第一部分HLA-DP、DQ基因多态性与福建汉族人群乙型肝炎病毒感染及其不同结局的关联中文摘要·····························································································7英文摘要·····························································································8材料与方法························································································9结果····························································································14讨论····························································································25第二部分HLA-DP基因多态性与中国人群肝癌相关性的Meta分析中文摘要····························································································27英文摘要····························································································28材料与方法·······················································································29结果····························································································30讨论····························································································34参考文献····························································································36综述····························································································40已发表论文························································································49致谢····························································································50-2-英汉缩略语名词对照（Abbreviations）英文缩写英文全称中文名称AFPalphafetoprotein甲胎蛋白ALTalanineaminotransferase丙氨酸氨基转移酶AsCAsymptomaticHBVCarrier无症状HBV携带者ASTGlutamic-Oxal(O)AceticTransaminase天冬氨酸氨基转移酶bpCHBBasePairChronicHepatitisB碱基对慢性乙型肝炎CGASCandidateGeneAssociationStudy候选基因关联研究DNADeoxyribonucleicAcid脱氧核糖核酸EDTAEthylenediamineTetraaceticAcid乙二胺四乙酸μlGWASMicrolitreGenomeWideAssociationStudy微升全基因组关联分析HBcAbHepatitisB