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finding best evidence for evidence-based best practice recommendations in health care the initial decision support system design精品.pdf

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finding best evidence for evidence-based best practice recommendations in health care the initial decision support system design精品

Knowl Inf Syst (2011) 29:159–201 DOI 10.1007/s10115-011-0439-8 REGULAR PAPER Finding best evidence for evidence-based best practice recommendations in health care: the initial decision support system design Nick Cercone · Xiangdong An · Jiye Li · Zhenmei Gu · Aijun An Received: 28 July 2008 / Revised: 13 June 2011 / Accepted: 8 August 2011 / Published online: 24 August 2011 © Springer-Verlag London Limited 2011 Abstract A major problem for Canadian health organizations is ﬁnding best evidence for evidence-based best practice recommendations. Medications are not always effectively used and misuse may harm patients. Drugs are the fastest-growing element of Canadian health care spending, second only to hospital spending. Three hundred million prescriptions are ﬁlled annually. Prescription drugs accounted for 5.8% of total health care spending in 1980 and close to 18% today. A primary long-term goal of this research is to develop a decision support system for evidence-based management, quality control and best practice recommen- dations for medical prescriptions. Our results will improve accessibility and management of information by: (1) building an prototype for adaptive information extraction, text and data mining from (online) documents to ﬁnd evidence on which to base best practices; and (2) employing multiply sectioned Bayesian networks (MSBNs) to infer a probabilistic interpreta- tion to validate evidence for recommendations; MSBNs provide this structure. Best practices to improve drug-related health outcomes; patients’ quality of life; and cost-effective use of medications by changing knowledge and behavior. This research will support next generation eHealth decision support systems, which routinely ﬁnd and verify evidence from multiple sources, leading to cost-effective use of drugs, improve patients’ quality of life and optimize drug-related health outcomes. Keywords Evidence-based best practices · Decision su