CLT老鼠控 制方案【策划稿】.pptVIP

急性与慢性药物比较Differentiation between Acute and Chronic 急性 Acute 1.对中枢神经 Effect to CNS 2.2-8小时死亡 Died within 2-8 hrs. 3. 会产生抗食性 Develop bait shyness. 4. 尸体多 More carcasses 5. 无解毒药 No antidote 6. 高浓度 High concentration of A.I (80%). 7. 无抗药性 No resistance 慢性 Chronic 1. 对维生素 Effect Vit-K Cycle 2.2-10天死亡 Died within 2-10 days 3. 无抗食性 No bait shyness 4. 尸体少 Less carcasses. 5. 有解毒药 Antidote 6. 低浓度 Low concentration ( 0.0025-0.005%) 7.有抗药性 (第一代) Resistance problem ( First generation) 杀鼠药历史 History of Rodenticides 急性 Acutes 慢性 Chronics Arsenic / Strychnine / Red squill Thallium sulphate / Zinc phosphate 氟乙酸钠 Sodium fluoroacetate 安鼠药 Antu Castrix 香豆素 Dicoumarin 杀鼠灵 Warfarin 氯杀鼠灵 Pival Coumachlor 敌鼠 Diphacinone Coumafuryl Fluoroacetamide 杀鼠迷 Coumatetralyl 1940 1950 杀鼠药历史 History of Rodenticides 急性 Acutes 慢性 Chronics 氯鼠酮 Chlorophacinone Norbormide a - 氯醛糖 Alphachloralose Pyriminil 骨化醇 Calciferol 敌拿鼠 Difenacoum 澳敌隆 Bromadiolone 澳敌拿鼠 Brodifacoum 大隆 Bromethalin 杀它仗 Flucoumafen 敌鼠 Difethialone 1960 1970 1980 三种杀鼠药 3 Classes of Rodenticide 单次用药, 见效快 Single-dose fast-action rodenticide eg. Zinc phosphide etc. 单次用药, 见效慢 Single-dose slow-action rodenticide eg. Difenacoum , Bromadiplone , Brodifacoum , Flocoumafen , Difethialone 多次用药, 见效慢 Multiple-dose slow-acting eg. Coumatetralyl , Warfarin 对白鼠的急性半数致死量Acute Oral LD50 of Several Anticoagulants to Albino Mus Musculus ( 25 g.) 抗凝血杀鼠药 半数致死量 活性成分 服药量(半数致死量) Anticoagulant LD50 (mg/kg) %A.I.) LD 50 (g.of bait) 第一代 First generation Diphacinone 141 0.005 70.5 Chlorophacinone 1.06 0.005 0.7 Coumatetralyl 2000 0.0375 1500 Warfarin 374 0.05 18.5 第二代 Second genera