jailed球囊对冠状动脉分叉病变介入治疗中分支血管开口及闭塞发生率的影响.docVIP

Jailed球囊对冠状动脉分叉病变介入治疗中分支血管开口及闭塞发生率的影响 　　[摘要] 目的 研究Jailed球囊??冠状动脉分叉病变介入治疗中分支血管开口及闭塞发生率的影响。方法 方便选取该院2014年1月―2015年12月期间进行冠状动脉分叉病变介入治疗的70例患者为研究对象。随机分成对照组与观察组，两组患者在年龄、性别、病史、病情等方面相似，具有可比性。两组患者的冠状动脉造影证实冠状动脉真性分叉病变，患者的主支进行单支架置入术，对照组患者的分支进行球囊对吻术或简单支架术，而观察组患者行Jailed球囊术。治疗前均已常规应用阿司匹林，氯吡格雷或替格瑞洛 未应用者给予术前给予300 mg阿司匹林肠溶片及300～600 mg氯吡格雷或180 mg替格瑞洛顿服。介入治疗后均采用每天口服氯吡格雷75 mg qd（替格瑞洛90 mg bid），最少坚持服用1年，阿司匹林肠溶片100 mg qn长期口服。对比分析两组患者并发症情况和术后不良事件情况，并比较两组患者介入治疗术参数（PCI操作时间 （min）、曝光时间（min）、造影剂用量（mL）、植入DES数量（枚）、手术费用（万）。结果 两组患者的并发症情况、术后半年病变血管狭窄情况差异无统计学意义；两组患者的介入治疗参数、术后半年内不良心血事件的发生率等差异有统计学意义（P 　　[关键词] Jailed球囊；冠状动脉分叉病变；血管开口 　　[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742（2016）12（c）-0007-03 　　[Abstract] Objective To study the effect of Jailed balloon on the incidence of branch vessel opening and occlusion in coronary bifurcation lesions. Methods Convenient selection 70 patients with coronary bifurcation lesions treated in our hospital from January 2014 to December 2015 were studied. Randomly divided into control group and observation group， the two groups of patients in the age， gender， history， illness and other aspects of similar， comparable. Two groups of patients with coronary angiography confirmed coronary bifurcation lesions， the main branch of patients with single stent implantation， the control group of patients with branch kiss surgery or simple stent balloon， and the observation group were treated with Jailed balloon. Before the treatment has been the routine use of aspirin or clopidogrel or ticagrelor was used for preoperative administration of Aspirin Enteric-coated Tablets 300 mg or 300～600 mg clopidogrel or 180 mg ticagrelor treatment. After interventional therapy were treated with daily oral clopidogrel 75 mg qd （ticagrelor 90 mg bid）， at least insist on taking a year， Aspirin Enteric-coated Tablets 100 mg qn orally. Results There was no significant difference in the first half of the two groups of patients with vascular stenosis and postoperative complications； there were statistically