胺碘酮联合美托洛尔治疗快速心律失常的疗效及安全性评估.docVIP

精品论文 参考文献 胺碘酮联合美托洛尔治疗快速心律失常的疗效及安全性评估 邵阳市医专附属医院 湖南邵阳 422000 　　【摘 要】目的：评估胺碘酮联合美托洛尔治疗快速心律失常的疗效及安全性。方法：选取2014年3月-2015年6月我院收治的60例快速心律失常患者作为研究对象，按随机分组原则将其分为对照组和治疗组，每组30例。在常规治疗基础上，对照组给予葡萄糖和胺碘酮治疗，治疗组在对照组基础上联合美托洛尔治疗。比较患者治疗前后心率、血压变化及临床效果。结果：治疗前两组患者的舒张压、心率及收缩压经比较差异无统计学意义（Plt;0.05）；治疗后治疗组的舒张压、收缩压及心率明显优于对照组，差异有统计学意义（Plt;0.05）；治疗组总有效率（96.67%）显著优于对照组（73.33%），差异有统计学意义（Plt;0.05）。结论：胺碘酮联合美托洛尔治疗快速心律失常的效果显著，且有效降低了发病率，缩短了治疗时间，缓解了病患病情，安全有效，值得在临床上应用并推广。 　　【关键词】胺碘酮； 美托洛尔； 快速心律失常 　　[Abstract] objective：to evaluate amiodarone with metoprolol therapy rapid arrhythmia efficacy and safety. Selection methods：March 2014-60 cases in June 2015 in our hospital rapid arrhythmia patients as the research object，according to the principle of random grouping will be divided into control group and treatment group，30 cases in each group. On the basis of conventional treatment，the control group given glucose and amiodarone treatment，treatment group with metoprolol therapy on the basis of in the control group. Comparison before and after treatment in patients with heart rate，blood pressure change and clinical effect. Results：two groups of patients before treatment of diastolic blood pressure，heart rate and systolic blood pressure there was no statistically significant difference by comparison（P lt; 0.05）；After treatment and diastolic and systolic blood pressure and heart rate of treatment group was obviously better than control group，the difference was statistically significant（P lt; 0.05）；Treatment group total effective rate（96.67%）were significantly better than the control group（73.33%），the difference was statistically significant（P lt; 0.05）. Conclusion：amiodarone with metoprolol therapy rapid arrhythmia effect is remarkable，and effectively reduce the incidence of a disease，shorten the treatment time，alleviate the patients condition，safe，effective and worth in the clinical application and promotion. 　　[Key words] amiodarone；Metoprolol；Rapid arrhythmia 　　 　　 　　近几年随着我国人民生活水平的不断提高，心血管等疾病的发病率也大幅度上升[1]。在