甲泼尼龙结合丙球蛋白在小儿急性重症支原体肺炎治疗中的应用评价.docVIP

精品论文 参考文献 甲泼尼龙结合丙球蛋白在小儿急性重症支原体肺炎治疗中的应用评价 资阳市雁江区妇幼保健计划生育服务中心儿科 641300 【摘 要】目的：分析并探索于小儿急性重症支原体肺炎治疗中以甲泼尼龙结合丙球蛋白联合用药的安全性及可行性分析。方法：随机选取2013年2月～2015年2月间我院门诊收治的小儿急性重症支原体肺炎患儿180例，双盲分为实验组和对照组，各90例，两组间一般资料差异；其中对照组单纯采用甲泼尼龙进行治疗，静脉滴注甲泼尼龙20mg/（kgmiddot;d），1次/d，加入5％葡萄糖100～250ml，1～2h静脉快速滴注；实验组患儿在常规治疗基础上，静脉滴注甲泼尼龙18mg/（kgmiddot;d），1次/d，加入5％葡萄糖100～250ml，静脉快速滴注，同时静滴丙球蛋白400mg/（kgmiddot;d），1次/d。比较两组患者治疗周期中的临床治疗效果、啰音消失时间、咳嗽减轻时间、体温恢复时间等临床指标差异。结果：实验数据显示，实验组出现好转即患儿啰音消失，咳嗽减轻及体温恢复等所需治疗时间明显快于对照组患儿，且实验组的治疗总有效率达94.44％远高于对照组。结论：在对小儿急性重症支原体肺炎的治疗中，以甲泼尼龙与丙球蛋白联合用药可有效缩短患儿病程，减少该病症对患儿脏器的损伤，具有较高的临床价值。 【关键词】甲泼尼龙；丙球蛋白；患儿；急性重症支原体肺炎；联合用药 [Abstract] Objective：to analyze and explore in the treatment of children with acute severe mycoplasma pneumonia with methylprednisolone combined with the safety and feasibility analysis of immunoglobulin combination therapy. Methods：randomly selected children with acute severe mycoplasma pneumonia from February 2013 to February 2015 in our hospital 180 cases，double-blind divided into experimental group and control group，90 cases in each general information，the difference between the two groups；the control group was treated with methylprednisolone treatment，intravenous methylprednisolone 20mg/（kg - D），1 /d，adding 5% glucose 100 ~ 250ml，1 ~ 2H intravenous drip；experiment Groups of children on the basis of routine treatment，intravenous methylprednisolone 18mg/（kg - D），1 /d，adding 5% glucose 100 250ml，intravenous drip，while intravenous immunoglobulin 400mg/（kg - D），the clinical therapeutic effect of 1 /d. were compared between the two groups in the cycle. Reduce cough disappeared time，time，temperature recovery time and other clinical indicators of differences. Results：the experimental data showed that the experimental group has improved that children with rales，cough and body temperature recovery required treatment time significantly faster than the control group，and the treatment of the experimental group total effective rate was 94 The 44% is much higher than that of contro