甲泼尼龙联合肾上腺素治疗Ⅲ度喉梗阻的临床观察.docVIP

精品论文 参考文献 甲泼尼龙联合肾上腺素治疗Ⅲ度喉梗阻的临床观察 罗显荣 吴蓉 （仪陇县人民医院 四川仪陇 637600） 【摘要】目的 观察甲泼尼龙联合雾化肾上腺素治疗Ⅲ度喉梗阻的疗效。 方法 治疗组20例急性喉炎合并Ⅲ度喉梗阻患儿，应用小剂量甲泼尼龙静脉注射联合氧气驱动雾化吸入肾上腺素治疗。对照组应用地塞米松静脉注射，同时雾化吸入地塞米松治疗。 结果 入院经治疗1h后，治疗组20例患儿缺氧症状均得到改善，有效率100﹪，对照组4例病情好转,有效率仅为20.0﹪。治疗2h后，治疗组有效率100﹪，对照组有效率60.0﹪。两组疗效比较差异有统计学意义（P＜0.05）。结论 小剂量甲泼尼龙联合雾化吸入肾上腺素治疗Ⅲ度喉梗阻起效快，疗效明显优于地塞米松静脉注射并同时吸入地塞米松，且不良反应小，可避免气管切开，值得临床推广使用。 【关键词】 甲泼尼龙 肾上腺素 喉梗阻 【中图分类号】R45 【文献标识码】A 【文章编号】2095-1752（2012）13-0387-02 Clinical observation of Methylprednisolone combined with Epinephrine in treating degree Ⅲ laryngeal obstruction LUO Xian-rong, WU Rong （The Peoplersquo;s Hospital of Yilong, Yilong 637600,Sichuan ） 【Abstract】Objective To observe the efficacy in the treatment of degree Ⅲ laryngeal obstruction with methylprednisolone combined with nebulized epinephrine. Methods Twenty children of acute laryngitis with degree Ⅲ laryngeal obstruction in treatment group used a small dose of intravenous methylprednisolone combined with inhalation of oxygen-driven nebulized epinephrine. Twenty children in the control group used intravenous and synchronously nebulized dexamethasone. Both groups received antibiotics as adjunctive therapy at the same time. Results After one hourrsquo;s treatment, in the treatment group, all childrenrsquo;s hypoxia symptoms improved with a 100﹪ effective rate. While in the control group, only four childrenrsquo;s hypoxia symptoms improved with a 20.0﹪ effective rate. After two hours of treatment, the effective rate in control group was raised to 60.0﹪. The difference between the efficacy of the two groups was statistically significant （P＜0.05）. Conclusions The treatment of degree Ⅲ laryngeal obstruction with a small dose of methyprednisolone combined with inhalation of nebulized epinephrine is effective and can avoid a tracheotomy. The efficacy of the treatment is obviously higher than intravenous and synchronously nebulized dexamethasone and deserves complication