奥美拉唑联合奥曲肽对治疗肝硬化食管胃底静脉曲张破裂出血的效果评价.docVIP

精品论文 参考文献 奥美拉唑联合奥曲肽对治疗肝硬化食管胃底静脉曲张破裂出血的效果评价 姜海燕 （湖北省丹江口市武当山特区医院 442714） 　　【摘要】目的：探讨在肝硬化食管胃底静脉曲张破裂出血的临床治疗中对奥美拉唑及奥曲肽进行联合用药的效果。方法：将2011~2013年我院收治的48例肝硬化食管胃底静脉曲张破裂出血患者进行随机数字表法分组，每组各24例，将其中单用奥曲肽治疗者归为对照组，将给予奥曲肽及奥美拉唑进行联合治疗者归为观察组，评估两组的临床治疗结局，总结治疗经验。结果：观察组经联合用药后，可取得91.7%的临床疗效，较之对照组的70.8%，差异明显（P＜0.05）。治疗期间观察组有2例（8.3%）出现不适，较之对照组略占优势（P＞0.05）。结论：给予肝硬化食管胃底静脉曲张破裂出血患者提供奥美拉唑及奥曲肽联合疗法进行治疗，能够取得更为理想的临床疗效，且具有安全、可靠的特点，是今后医院单位提高本病救治水平的关键，建议普及。 　　【关键词】奥美拉唑 奥曲肽 肝硬化 食管胃底静脉曲张破裂出血 　　【中图分类号】R453 【文献标识码】A 【文章编号】1672-5085（2014）10-0015-01 　　Omeprazole combined with octreotide for the treatment of cirrhosis and esophageal varices bleeding Evaluation 　　【Abstract】Objective:To investigate cirrhosis and esophageal varices bleeding clinical treatment for drug omeprazole and joint effect of octreotide.Methods:2011~2013 in our hospital 48 cases of esophageal variceal bleeding cirrhotic patients were randomly divided into groups of 24 cases each , which will be owned by a single treatment with octreotide in the control group will be given octreotide and omeprazole combination therapy were classified as observation group to assess clinical outcomes between the two groups ,summarize the treatment experience. Results: The study group after combination therapy, the clinical efficacy of 91.7% can be achieved,and 70.8% compared with the control group,the difference was significantly (Plt;0.05).Observed during treatment group 2 patients (8.3%) discomfort, slight advantage compared to the control group (Pgt;0.05).Conclusion: give cirrhotic patients with esophageal varices bleeding provide omeprazole and octreotide therapy treatment, clinical efficacy can be achieved more desirable and safe,and reliable,hospital units to improve the future treatment of this disease critical level , the proposed universal. 　　【Key words】omeprazole octreotide cirrhosis bleeding esophageal varices 　　肝硬化食管胃底静脉曲张破裂出血（EGVB）属于肝硬化门脉高压的一种严重性并发症，同时也是临床上相对常见的一种急症。一旦发病，患者初次出血后死亡的可