头孢噻肟联合左氧氟沙星治疗急性肾盂肾炎的疗效评价.docVIP

精品论文 参考文献 头孢噻肟联合左氧氟沙星治疗急性肾盂肾炎的疗效评价 （成都锦欣中医医院 四川 成都 610000） 　　【摘要】 目的 探讨头孢噻肟和左氧氟沙星治疗急性肾盂肾炎的临床疗效。方法 选取我院2015年1月-2015年6月收治的76例急性肾盂肾炎患者，随机分为两组，对照组采用左氧氟沙星治疗，实验组采用头孢噻肟联合左氧氟沙星治疗，连续治疗14天后，比较两组患者的治疗效果及症状消失时间。 结果 两组患者的疗效相比，实验组的治疗有效率97.37%，对照组的有效率81.58%，两组总有效率相比较，差异具有统计学意义（Plt;0.05）；两组膀胱刺激症状消失时间相比较，实验组时间更短，差异具有统计学意义（plt;0.05）。 结论 采用头孢噻肟联合左氧氟沙星治疗急性肾盂肾炎，能显著改善临床症状，增强疗效，是较为理想的治疗方案，值得临床推广使用。 　　【关键词】 头孢噻肟；左氧氟沙星；急性肾盂肾炎 　　curative effect evaluation of Cefotaxime and levofloxacin in treatment of acute pyelonephritis 　　Zhu Hong-ling 　　(Chengdu Chinese medicine hospital kam hin, Chengdu 610000，Sichuan Province,China) 　　【Abstract】 Objective to investigate the clinical curative effect of Cefotaxime and levofloxacin on treatment of acute pyelonephritis. Methods 76 cases of patients with acute pyelonephritis from January 2015 to June 2015,were randomly divided into two groups. control group were treated by levofloxacin, experimental group were treated by cefotaxime and levofloxacin , two groups were treated for 14 days, the therapeutic effect and symptoms disappear time were observed and compared in two groups. Results comparision of the clinical curative effect of the two groups, the total effective rate in experimental group was 97.37%, 81.58% in the control group. there were significant differences between the two groups (Plt;0.05); the disappear time of Bladder irritation symptoms were compared in two groups ,the disappear time in experimental group was shorter , there were significant differences between the two groups (Plt;0.05). Conclusions Using Cefotaxime and levofloxacin on treatment of acute pyelonephritis can significantly improve the clinical symptoms, enhance the curative effect. it was the ideal treatment worthy of clinical use. 　　【Key Words】 Cefotaxime；levofloxacin；Acute pyelonephritis 　　肾盂肾炎是指肾脏及肾盂的炎症，大都由细菌感染引起，常伴有下尿路炎症。各种原因引起的膀胱-输尿管反流和肾内反流是致病菌进一步上行引起肾脏炎症及肾盂肾炎的重要病理基础。根据临床病程及症状，肾盂肾炎可分为急性和慢性两期。急性肾盂肾炎病变可分为单侧或双侧，可轻可重，轻者仅累及肾盂粘膜，严重者可致坏死性乳头炎[1]。急性肾盂肾炎主要致病菌为革兰阴性杆菌，以大肠埃希菌最