含糖透析液对维持性血液透析病人血压的影响.docVIP

精品论文 参考文献 含糖透析液对维持性血液透析病人血压的影响 王天智 李文静 刘翠红 　　（石家庄市第三医院肾内科 河北 石家庄 050011） 　　【摘 要】目的：分析含糖透析液对维持性血液透析病人血压的影响。方法：将38例非糖尿病肾病的慢性血透患者随机分为2组，分别应用无糖和含糖透析液（葡萄糖浓度5mmol/L）进行血液透析治疗，比较并分析两组病人在透析过程中的血压变化情况。结果：透析前，两组病人血压基线值的比较无显著差异（P＞0.05）。透析过程中，两组病人的血压出现不同幅度的升高，且透析时间达4h后，无糖透析液治疗患者的平均收缩压显著高于含糖透析液治疗患者（P＜0.05）。含糖透析液治疗患者在透析过程中高血压发生率显著下降（P＜0.05）。结论：对维持性血液透析病人进行含糖透析液治疗，不仅能有效改善其自主神经系统功能，使胰岛素得以释放，血管得以舒张，而且还能有效降低高血压的发生率，因此，值得推广与应用。 　　【关键词】含糖透析液；维持性血液透析；血压 　　【中图分类号】R459.5；R544.1 【文献标识码】A 【文章编号】1003-5028（2015）5-0211-02 　　The influence of glucose-containing dialysate on blood pressure in maintenance hemodialysis patients 　　【Abstract】Objective: To explore the effect of glucose-containing dialysate on blood pressure in maintenance hemodialysis patients. Methods: 38 patients with non-diabetic nephropathy undergoing maintenance hemodialysis were randomly divided into two groups, to which dialysate containing 0 or 5mmol/L glucose was used respectively. The changes of blood pressure were detected during the process of dialysis. Result: There was no significant difference in blood pressure between two groups of patients before dialysis (Pgt; 0.05). In the processes of dialysis, blood pressure increased, and after 4 hours, the mean systolic blood pressure was significantly higher in the patients using glucose-free dialysate than glucose-containing dialysate (Plt;0.05). The use of glucose-containing dialysate resulted in a significant decrease in the incidence of hypertension (Plt;0.05). Conclusion: The use of glucose-containing dialysate can not only effectively improve the autonomic nervous system function, release insulin and relax blood vessels, but also effectively reduce the incidence of hypertension in patients with maintenance hemodialysis, and therefore is worthy of promotion and application. 　　【Key words】glucose-containing dialysate; maintenance hemodialysis; blood pressure 　　肾脏替代治疗是一种通过利用腹膜透析或血液透析来延长或挽救病人生命的过度方法，其中，血液透析是临床上较为常见的用于治疗肾功能衰竭的方法。目前，终末期肾病患者的逐年增加，使得维持性血液透析病人不再仅仅局限于因慢