川芎嗪辅助治疗慢性肺源性心脏病的临床疗效观察.docVIP

精品论文 参考文献 川芎嗪辅助治疗慢性肺源性心脏病的临床疗效观察 陆守彦 　　江苏省淮海农场医院 江苏盐城 224300 　　摘要：目的：观察川芎嗪对慢性肺心病患者临床疗效及血流变的影响。方法：选择2013年1月-2014年12月慢性肺源性心脏病患者44例，随机分成两组。对照组采取常规的治疗方法，观察组在对照组的基础上，应用川芎嗪注射液80mg静脉滴注 qd，14天为一疗程。观察两组患者的临床效果及血流变的变化。结果：①临床疗效：观察组显效率、总有效率为36.37%、86.37%，对照组显效率、总有效率为：18.18%、72.73%；②血流变检测结果：观察组治疗后血液粘稠度低、高切值分别为8.12plusmn;2.67、3.28plusmn;0.58；对照组治疗后血液粘稠度低、高切值分别为10.41plusmn;2.39、4.72plusmn;0.8。两组对应参数比较具有显著差异性（P＜0.05），有统计学意义。结论：川芎嗪辅助治疗慢性肺源性心脏病，能够有效的降低患者血液粘稠度和肺动脉压力、改善患者的心功能，起到标本兼治的临床效果，值得推广使用。 　　关键词：川芎嗪注射液；慢性肺源性心脏病；临床效果 　　[Abstract]Objective：To investigate the effects of tetramethylpyrazine on clinical efficacy in patients with chronic pulmonary heart disease and blood flow change.Methods：January 2013 - December 2014 44 patients with chronic pulmonary heart disease were randomly divided into two groups.The control group received conventional treatment，observation group in the control group based on the application of TMP intravenous injection 80mg qd，14 days for treatment.Changes were observed clinical effect and blood flow change.Results：① clinical efficacy：markedly effective observation group，the total effective rate was 36.37%，86.37%，the control group was efficient，the total effective rate：18.18%，72.73%；② changes in blood flow test results：the observation group after treatment of blood viscosity Consistency low and high shear values were 8.12 plusmn; 2.67，3.28 plusmn; 0.58；control group after treatment of low blood viscosity，high shear values were 10.41 plusmn; 2.39，4.72 plusmn; 0.8.The corresponding parameters between the two groups was significant difference（P lt;0.05），statistically significant.Conclusion：TMP adjuvant treatment of chronic pulmonary heart disease，can effectively reduce blood viscosity in patients with pulmonary arterial pressure and improve heart function in patients，played both the root causes of the clinical effect，should be introduced. 　　[Key words]：TMP injection；chronic pulmonary heart disease；clinical effect 　　慢性肺源性心脏病临床简称为慢性肺心病，是由肺组织、肺动脉血管或胸廓的慢性病变引起肺组织结构