酒石酸美托洛尔联用小剂量胺碘酮治疗心肌梗死后室性心律失常比较探究.docVIP

酒石酸美托洛尔联用小剂量胺碘酮治疗心肌梗死后室性心律失常比较探究 　　[摘要] 目的 探讨酒石酸美托洛尔与小剂量胺碘酮联合治疗心肌梗死后室性心律失常的有效性和成功率。 方法 回顾性分析本院收治的150例心肌梗死后室性心律失常患者的临床诊治资料，根据治疗方法分为对照组和联合组，其中对照组72例采用酒石酸美托洛尔单一治疗方案，联合组78例采用小剂量胺碘酮联合酒石酸美托洛尔治疗，对比两组治疗后的各项心脏参数、效果及不良反应发生情况。 结果 联合组患者的心率、LVEF%、P-R间期及QRS间期均较对照组平稳，两组差异有统计学意义（P0.05）。 结论 酒石酸美托洛尔联合胺碘酮治疗心肌梗死后室性心律失常，安全性好，临床效价比较高。 [关键词] 酒石酸美托洛尔；胺碘酮；心肌梗死；室性心律失常 [中图分类号] R972+.2 [文献标识码] A [文章编号] 1674-4721（2013）11（c）-0089-02 Comparative study of metoprolol tartrate combined with low-dose amiodarone in the treatment of ventricular arrhythmias after myocardial infarction PAN De-hui Department of Cardiovascular Medicine，the Fifth People′s Hospital of Foshan City in Guangdong Province，Foshan 528211，China [Abstract] Objective To explore the effectiveness and success rate of metoprolol tartrate combined with low-dose amiodarone in the treatment of ventricular arrhythmias after myocardial infarction.Methods Clinical data of 150 cases of ventricular arrhythmias after myocardial infarction admitted to the author′s hospital was retrospectively analyzed，and were divided into control group and combined group according to the different trentmnet method，72 cases in the control group were given metoprolol tartrate single treatment while 78 cases in the combined group were given combined treatment of low-dose amiodarone and metoprolol tartrate.Cardiac parameters，effectiveness and adverse events of the two groups were compared.Results The heart rate，LVEF%，P-R interval and QRS duration was signigicantly more stable in the combined group than that in the control group （P0.05）.Conclusion Metoprolol tartrate combined with amiodarone therapy in the treatment of patients with ventricular arrhythmias after myocardial infarction is safe and has higer clinical cost-effectiveness. [Key words] Metoprolol tartrate；Amiodarone；Myocardial infarction；Ventricular arrhythmias 心肌梗死后并发症情况是临床常见的危急重症，临床治疗需要谨慎选择有效的药物和辅助措施[1]，其中室性心律失常常合并其他严重的心力衰竭等问题，单一药物治疗效果不佳，本研究探讨联合两种药物从降低心律失常发生机制上进行治疗，效果显著，现报道如下。 1