a randomised placebo-controlled trial of a traditional chinese herbal formula in the treatment of primary dysmenorrhoea中国传统草药配方的随机安慰剂对照试验治疗原发性痛经.pdfVIP
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a randomised placebo-controlled trial of a traditional chinese herbal formula in the treatment of primary dysmenorrhoea中国传统草药配方的随机安慰剂对照试验治疗原发性痛经
A Randomised Placebo-Controlled Trial of a Traditional
Chinese Herbal Formula in the Treatment of Primary
Dysmenorrhoea
1 2 3 4 5 6 7 3
Lan Lan Liang Yeh *, Jah-Yao Liu , Kao-Si Lin , Yu-Shen Liu , Jeng-Min Chiou , Kung-Yee Liang , Te-Feng Tsai , Li-Hsiang Wang , Chiung-Tong
Chen8, Ching-Yi Huang1
1 Division of Clinical Research, National Health Research Institutes, Zhunan, Taiwan, 2 Department of Obstetrics and Gynaecology, Tri-Service General
Hospital of National Defense Medical Centre, Taipei, Taiwan, 3 Department of Chinese Medicine, Tri-Service General Hospital of National Defense
Medical Centre, Taipei, Taiwan, 4 Section of Obstetrics and Gynaecology, Taipei Municipal Hospital Zhongxiao Branch, Taipei, Taiwan, 5 Institute of
Statistical Science of Academia Sinica, Taipei, Taiwan, 6 Division of Biostatistics and Bioinformatics, National Health Research Institutes, Zhunan,
Taiwan, 7 Section of Chinese Medicine, Taipei Municipal Hospital Zhongxiao Branch, Taipei, Taiwan, 8 Division of Biotechnology and Pharmaceutical
Research, National Health Research Institutes, Zhunan, Taiwan
Background. Most traditional Chinese herbal formulas consist of at least four herbs. Four-Agents-Decoction (Si Wu Tang) is
a documented eight hundred year old formula containing four herbs and has been widely used to relieve menstrual discomfort
in Taiwan. However, no specific effect had been systematically evaluated. We applied Western methodology to assess its
effectiveness and safety for primary dysmenorrhoea and to evaluate the compliance and feasibility for a future trial.
Methodology/Principal Findings. A randomised, double-blind, placebo-controlled, pilot clinical trial was conducted in an ad
hoc clinic setting at a teaching hospital in Taipei, Taiwan.
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