a higher-order generalized singular value decomposition for comparison of global mrna expression from multiple organisms高阶广义奇异值分解进行比较,从多个生物全球mrna的表达.pdfVIP
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a higher-order generalized singular value decomposition for comparison of global mrna expression from multiple organisms高阶广义奇异值分解进行比较,从多个生物全球mrna的表达
A Higher-Order Generalized Singular Value
Decomposition for Comparison of Global mRNA
Expression from Multiple Organisms
1 2 3 4
Sri Priya Ponnapalli , Michael A. Saunders , Charles F. Van Loan , Orly Alter *
1 Department of Electrical and Computer Engineering, University of Texas at Austin, Texas, United States of America, 2 Department of Management Science and
Engineering, Stanford University, Stanford, California, United States of America, 3 Department of Computer Science, Cornell University, Ithaca, New York, United States of
America, 4 Scientific Computing and Imaging (SCI) Institute and Departments of Bioengineering and Human Genetics, University of Utah, Salt Lake City, Utah, United
States of America
Abstract
The number of high-dimensional datasets recording multiple aspects of a single phenomenon is increasing in many areas of
science, accompanied by a need for mathematical frameworks that can compare multiple large-scale matrices with different
row dimensions. The only such framework to date, the generalized singular value decomposition (GSVD), is limited to two
matrices. We mathematically define a higher-order GSVD (HO GSVD) for N$2 matrices Di [Rmi |n , each with full column
T
rank. Each matrix is exactly factored as D = U S V , where V, identical in all factorizations, is obtained from the eigensystem
i i i
SV = VL of the arithmetic mean S of all pairwise quotients A A {1 of the matrices A ~DT D , i?j . We prove that this
i j i i i
decomposition extends to
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