肝硬化并发自发性腹膜炎病原菌及药敏分析（Pathogenic bacteria and drug sensitivity analysis of spontaneous bacterial peritonitis in cirrhosis）.docVIP

肝硬化并发自发性腹膜炎病原菌及药敏分析（Pathogenic bacteria and drug sensitivity analysis of spontaneous bacterial peritonitis in cirrhosis） Cirrhosis of liver: analysis of pathogenic bacteria and drug sensitivity of cirrhosis with spontaneous peritonitis Date: December 28, 2010 [Abstract] Objective: to analyze the pathogenic bacteria and their drug resistance in cirrhotic patients with spontaneous peritonitis, and to guide the clinical use. Methods: the distribution and drug resistance of pathogens positive for ascites in patients with cirrhosis and spontaneous peritonitis in our department from February to May 2010 were analyzed retrospectively. Results: 81 specimens were detected by bacterial G- bacilli (a total of 61 cases, accounting for 75%), Escherichia coli, Klebsiella pneumoniae is rare, Enterobacter bacteria to Amikacin, levofloxacin, ceftazidime, Cefoperazone / sulbactam and low drug resistance, no drug resistance to imipenem. Gram positive bacteria were detected in 20 cases (25%), more Staphylococcus epidermidis, and lower resistance to three or four generation cephalosporins. Conclusion: the ascites samples in the isolated bacteria were mostly opportunistic pathogen types, strong drug resistance, pathogen detection and drug resistance test is very important to clinical work on ascites samples, according to the drug sensitivity test to select antibiotics is very important. Keywords cirrhosis; spontaneous peritonitis; pathogens; antibacterial agents; Spontaneous peritonitis (SBP) is a common complication in patients with advanced cirrhosis. It is one of the major factors leading to exacerbations and even death. Timely and rational use of antibiotics is the key to treatment. In the actual work of ascites bacterial culture positive rate is not high, this paper discusses 81 cases of bacterial culture from February ~2010 year in May in our hospital in patients with cirrhosis and ascites peritonitis, and analyze the pathogenic bacteria, to guide clinical work. 1 data and methods