nervous necrosis virus replicates following the embryo development and dual infection with iridovirus at juvenile stage in grouper后神经坏死病毒复制胚胎发展和双重感染虹彩在石斑鱼的幼年期.pdfVIP

Nervous Necrosis Virus Replicates Following the Embryo Development and Dual Infection with Iridovirus at Juvenile Stage in Grouper 1,2,3. 1. 1,3 1 4,5 Hsiao-Che Kuo , Ting-Yu Wang , Hao-Hsuan Hsu , Peng-Peng Chen , Szu-Hsien Lee , Young- 1,2,3 1 6 7,8 4,5,9 Mao Chen , Tieh-Jung Tsai , Chien-Kai Wang , Hsiao-Tung Ku , Gwo-Bin Lee *, Tzong- Yueh Chen1,2,3* 1 Laboratory of Molecular Genetics, Institute of Biotechnology, National Cheng Kung University, Tainan, Taiwan, 2 Research Center of Ocean Environment and Technology, National Cheng Kung University, Tainan, Taiwan, 3 Agriculture Biotechnology Research Center, National Cheng Kung University, Tainan, Taiwan, 4 Institute of Nanotechnology and Microsystems Engineering, National Cheng Kung University, Tainan, Taiwan, 5 Department of Engineering Science, National Cheng Kung University, Tainan, Taiwan, 6 Division of Environmental Health and Occupational Medicine, National Health Research Institutes, Zhunan, Miaoli, Taiwan, 7 Research Division I, Taiwan Institute of Economic Research, Taipei, Taiwan, 8 Office for Energy Strategy Development, National Science Council, Taipei, Taiwan, 9 Department of Power Mechanical Engineering, National Tsing Hua University, Hsinchu, Taiwan Abstract Infection of virus (such as nodavirus and iridovirus) and bacteria (such as Vibrio anguillarum) in farmed grouper has been widely reported and caused large economic losses to Taiwanese fish aquaculture industry since 1979. The multiplex assay was used to detect dual viral infection and showed that only nervous necrosis virus (NNV)