nanometer-scale sizing accuracy of particle suspensions on an unmodified cell phone using elastic light scattering纳米粒子悬浮液的分级精度未经修改的手机使用弹性光散射.pdfVIP

Nanometer-Scale Sizing Accuracy of Particle Suspensions on an Unmodified Cell Phone Using Elastic Light Scattering 1 1 1,2 Zachary J. Smith *, Kaiqin Chu , Sebastian Wachsmann-Hogiu * 1 Center for Biophotonics Science and Technology, University of California Davis, Sacramento, California, United States of America, 2 Department of Pathology and Laboratory Medicine, University of California Davis, Sacramento, California, United States of America Abstract We report on the construction of a Fourier plane imaging system attached to a cell phone. By illuminating particle suspensions with a collimated beam from an inexpensive diode laser, angularly resolved scattering patterns are imaged by the phone’s camera. Analyzing these patterns with Mie theory results in predictions of size distributions of the particles in suspension. Despite using consumer grade electronics, we extracted size distributions of sphere suspensions with better than 20 nm accuracy in determining the mean size. We also show results from milk, yeast, and blood cells. Performing these measurements on a portable device presents opportunities for field-testing of food quality, process monitoring, and medical diagnosis. Citation: Smith ZJ, Chu K, Wachsmann-Hogiu S (2012) Nanometer-Scale Sizing Accuracy of Particle Suspensions on an Unmodified Cell Phone Using Elastic Light Scattering. PLoS ONE 7(10): e46030. doi:10.1371/journal.pone.0046030 Editor: Christof Markus Aegerter, University of Zurich, Switzerland Received June 22, 2012; Accepted August 28, 2012; Published October 2, 2012 Copyright: 2012 Smith et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which perm