mykaryoview a light-weight client for visualization of genomic datamykaryoview轻量级客户机基因组数据的可视化.pdfVIP
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mykaryoview a light-weight client for visualization of genomic datamykaryoview轻量级客户机基因组数据的可视化
myKaryoView: A Light-Weight Client for Visualization of Genomic Data 1 2 3 4,5 2 Rafael C. Jimenez , Gustavo A. Salazar , Bernat Gel , Joaquin Dopazo , Nicola Mulder , Manuel Corpas6* 1 European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom, 2 Computational Biology Group, Department of Clinical ` ´ Laboratory Sciences, IIDMM, University of Cape Town, Cape Town, South Africa, 3 Universitat Politecnica de Catalunya, Barcelona, Spain, 4 Centro de Investigacion ´ Prıncipe Felipe, Valencia, Spain, 5 Functional Genomics Node (INB), CIPF, Valencia, Spain, 6 Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom Abstract The Distributed Annotation System (DAS) is a protocol for easy sharing and integration of biological annotations. In order to visualize feature annotations in a genomic context a client is required. Here we present myKaryoView, a simple light-weight DAS tool for visualization of genomic annotation. myKaryoView has been specifically configured to help analyse data derived from personal genomics, although it can also be used as a generic genome browser visualization. Several well- known data sources are provided to facilitate comparison of known genes and normal variation regions. The navigation experience is enhanced by simultaneous rendering of different levels of detail across chromosomes. A simple interface is provided to allow
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