hypertension and maternal–fetal conflict during placental malaria高血压和母胎冲突期间胎盘疟疾.pdfVIP

PLoS MEDICINE Hypertension and Maternal–Fetal Conflict during Placental Malaria 1,2 1,3,4,5 5 1,2 1,2,6* Atis Muehlenbachs , Theonest K. Mutabingwa , Sally Edmonds , Michal Fried , Patrick E. Duffy 1 MOMS Project, Seattle Biomedical Research Institute, Seattle, Washington, United States of America, 2 University of Washington, Seattle, Washington, United States of America, 3 London School of Hygiene and Tropical Medicine, London, United Kingdom, 4 National Institute for Medical Research, Dar es Salaam, Tanzania, 5 Muheza Designated District Hospital, Muheza, Tanzania, 6 Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America Funding: This work was supported A B S T R A C T by funds from the Bill and Melinda Gates Foundation and NIH R01AI52059 (to PED), and the American Medical Association Background Foundation (to AM). AM was also supported by NIH training grant Malaria and hypertension are major causes of maternal mortality in tropical countries, T32HL07312. The funders had no especially during first pregnancies, but evidence for a relationship between these syndromes is role in study design, data collection contradictory. and analysis, decision to publish, or preparation of the manuscript. Competing Interests: The authors Methods and Findings have declared that no competing interests exist. In a cross-sectional survey of Tanzanian parturients, the rate of hypertension was similar in