hiv-prevalence in tuberculosis patients in germany, 2002–2009 an estimation based on hiv and tuberculosis surveillance data肺结核患者的艾滋病毒感染率在德国,2002 - 2009年的估计基于艾滋病和结核病监测数据.pdfVIP

HIV-Prevalence in Tuberculosis Patients in Germany, 2002–2009: An Estimation Based on HIV and Tuberculosis Surveillance Data 1 2 1 2 Lena Fiebig *, Christian Kollan , Barbara Hauer , Barbara Gunsenheimer-Bartmeyer , Matthias an der 2 2 1 Heiden , Osamah Hamouda , Walter Haas 1 Respiratory Infections Unit, Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany, 2 HIV/AIDS, STI and Blood-borne Infections Unit, Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany Abstract Tuberculosis (TB) and HIV comorbidity is a major challenge in TB prevention and control but difficult to assess in Germany as in other countries, where data confidentiality precludes notifying the HIV status of TB patients. We aimed to estimate the HIV-prevalence in TB patients in Germany, 2002–2009, and to characterize the HIV/TB patients demographically. Data from the long-term observational open multicentre cohort ClinSurv HIV were used to identify incident TB in HIV-positive individuals. We assessed the cohort’s coverage for the nationwide HIV-positive population by contrasting ClinSurv HIV patients under antiretroviral therapy (ART) with national HIV patient numbers derived from ART prescriptions (data by Insight Health; available for 2006–2009). The HIV-prevalence in TB patients was calculated as the number of HIV/TB cases projected for Germany over all culture-positive TB notifications. From 2002 to 2009, 298 of 15,531 HIV-positive patients enrolled in the ClinSurv HIV cohort were diagnosed with TB. A 21% cohort coverage was determined. The annual estimates of the HIV-prevalence in TB patients w