gene expression profiling of human decidual macrophages evidence for immunosuppressive phenotype基因表达分析人类蜕膜巨噬细胞的免疫抑制表型的证据.pdfVIP
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gene expression profiling of human decidual macrophages evidence for immunosuppressive phenotype基因表达分析人类蜕膜巨噬细胞的免疫抑制表型的证据
Gene Expression Profiling of Human Decidual Macrophages: Evidence for Immunosuppressive Phenotype 1 ¨ 1 2 3 4 ¨ Charlotte Gustafsson *, Jenny Mjosberg , Andreas Matussek , Robert Geffers , Leif Matthiesen , Goran 4 5,6 7 1 Berg , Surendra Sharma , Jan Buer , Jan Ernerudh 1 Division of Clinical Immunology, Unit for Autoimmunity and Immune Regulation (AIR), Department of Clinical and Experimental Medicine, Faculty of Health Sciences, ¨ ¨ ¨ University Hospital, Linkoping, Sweden, 2 Department of Clinical Microbiology, County Hospital Ryhov, Jonkoping, Sweden, 3 Mucosal Immunity, Helmholtz Centre for ¨ Infection Research (HCI), Braunschweig, Germany, 4 Division of Gynecology and Obstetrics, Faculty of Health Sciences, University Hospital, Linkoping, Sweden, 5 Department of Pediatrics, Brown University and Women and Infants’ Hospital of Rhode Island, Providence, Rhode Island, United States of America, 6 Department of Pathology, Brown University and Women and Infants’ Hospital of Rhode Island, Providence, Rhode Island, United States of America, 7 Institute of Medical Microbiology, University Hospital Essen, Essen, Germany Abstract Background: Although uterine macrophages are thought to play an important regulatory role at the maternal-fetal interface, their global gene expression profile is not known. Methodology/Principal Findings: Using micro-array comprising appr
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