高同型半胱氨酸血症与短暂性脑缺血发作的相关性.pdfVIP

第32卷 黑 龙 江 医 学 V01．32．No．7 2OO8年第7期 HEI LONG JIANG MEDICAL J0URNAL Ju1．2OO8 481 · 论著· 高同型半胱氨酸血症与短暂性脑缺血发作的相关性 田 虹 ，辛晓敏 (1．哈尔滨医科大学，黑龙江哈尔滨 150080；2．哈尔滨医科大学第一临床医学院实验诊断教研室，黑龙江哈尔滨150001) 摘要：日的 探讨高同型半胱氨酸血症(HHey)与短暂性脑缺血发作(TiA)的相关性。方法 对8O例 TIA患者(40例颈内动脉系统TIA、40例椎一基底动脉系统瞰 )和40例健康者进行血浆Hey及血脂检测。 结果 颈内动脉系统TIA和椎一基底动脉系统TIA患者的Hey水平均高于对照组，差异有显著性(P O．05)，且两者之间比较亦有显著性差异(PO．05)。结论 血浆Hey水平与TLA有关，且与颈内动脉系统 TLA关系更加密切，是TIA的独立危险因素。 关键词：短暂性脑缺血发作；高同型半胱氨酸血症；血脂 学科分类代码：320．1160 中图分类号：R446 文献标识码：A 文章编号：1004—5775(2008)07—0481—02 Study on the Relationship Between Hyperhomocysteinemia and TIA TIAN Hong，XIN Xiao～min (The Fouth Clinical Medical College ofHarbin Medical University，Harbin 150001，China) Abstrast：Objective To investigate the relationship between Hyperhomocysteinemia(HHey)and transient ischemie at— tacks(TIA)．Methods Plasm Hcy and blood—lipid were tested in 80 patients with瞰 (40 patients inⅡA were caused by internal carotic artery System and the other 40 ones were caused by vertebro—basilar artery system)and 40 healthy people only for physical examination．Results 1he patients isⅡA by internal carotid artery System or vertebro — basilar artery system had higher standards of plasm concentration of Homocysteine than the control group(P 0．05)． e standards of plasm concen~afion of Homocysteine in the patients in TIA by intemal carotid artery System are sii~nifieanfly different from the ones in TIA by vertebro—basilar artery system(P0．05)．Conclusion There is an association between plasm concentration of Hcy and TIA，and TIA by intemal carotid artery iS more significantly cot— related．There is no association between the level of plasma Hcy and blood—lipid．Plasma Hcy Can be one of the inde— pendent risk factors for Key words：TIA；Hyperhomocystei