肾复康胶囊联合百令胶囊治疗慢性肾小球肾炎的疗效观察.pdf

现代药物与临床 Drugs Clinic 第 31 卷 第 6 期 2016 年 6 月 ·823 · 肾复康胶囊联合百令胶囊治疗慢性肾小球肾炎的疗效观察 张文玉，李金萍，常文秀 天津市第一中心医院 肾内科，天津 300192 摘 要：目的 观察肾复康胶囊联合百令胶囊治疗慢性肾小球肾炎的疗效。方法 选取 2012 年 1 月—2015 年 12 月在天津 市第一中心医院肾内科就诊且确诊为慢性肾小球肾炎患者 95 例，随机分为对照组（48 例）和治疗组（47 例）。对照组患者 在常规治疗同时口服百令胶囊，5 粒/次，3 次/d 。治疗组在对照组的基础上口服肾复康胶囊，4 粒/次，3 次/d 。两组患者均 连续治疗 12 周。观察记录两组患者的临床总有效率、治疗前后 24 h 尿蛋白定量、尿红细胞计数（RBC ）、尿素氮（BUN ）、 血肌酐（Scr）的水平变化。结果 治疗后，对照组和治疗组总有效率分别为 85.42%、93.62%，两组差异比较具有统计学意 义（P ＜0.05 ）；两组患者的24 h 尿蛋白、RBC 、BUN 和 Scr 水平均显著降低，同组治疗前后差异具有统计学意义（P ＜0.05 ）； 且治疗组患者降低程度更为明显，两组比较差异具有统计学意义（P ＜0.05 ）。结论 肾复康胶囊联合百令胶囊治疗慢性肾小 球肾炎具有良好的疗效，能够改善肾功能指标，具有一定的临床推广应用价值。 关键词：肾康复胶囊；百令胶囊；慢性肾小球肾炎；疗效 中图分类号：R983 文献标志码：A 文章编号：1674 - 5515(2016)06 - 0823 - 03 DOI: 10.7501/j.issn.1674-5515.2016.06.021 Clinical observation of Shenfukang Capsules combined with Corbrin Capsules in treatment of chronic glomerulonephritis ZHANG Wen-yu, LI Jin-ping, CHANG Wen-xiu Department of Nephrology, Tianjin First Center Hospital, Tianjin 300192, China Abstract: Objective To observe the efficacy of Shenfukang Capsules combined with Corbrin Capsules in treatment of chronic glomerulonephritis. Methods Patients (95 cases) with chronic glomerulonephritis in Tianjin First Center Hospital from January 2012 to December 2015 were divided into control (48 cases) and treatment (47 cases) groups. The patients treated with western conventional treatment in the control group were po administered with Corbrin Capsules, 5 grains/time, three times daily. Patients in the treatment group were po administered with Shenfukang Capsules on the basis of control group, 4 grains/time, three times daily. The patients in two groups were treated for 12 weeks. After treatment, the clinical efficacies were evaluated, and the changes of 24 h urine protein, RBC, BUN, and Scr before and after treatment in two groups were compared. Res