中药穴位贴敷作用机理研究概况.pdfVIP

·134· Chinese Journal of Information on TCM Mar.2017 Vol.24 No.3 中药穴位贴敷作用机理研究概况 贺艳萍 1，肖小芹 1，邓桂明 2，欧阳林旗 2，陈镇 2，张志国 2 1.湖南中医药大学，湖南 长沙 410208；2.湖南中医药大学第一附属医院，湖南 长沙 410007 摘要：中药穴位贴敷历史悠久，临床疗效确切。本文基于中医理论的整体观和经络学说，从药物对机体的 局部刺激、经络传导、透皮吸收 3 方面阐述中药穴位敷贴的作用机理，并结合中药经皮给药系统、代谢组学、 药效物质基础等研究热点，提出中医药系统生物学这一新的研究模式。 关键词：穴位敷贴疗法；作用机理；中医药系统生物学；综述 DOI：10.3969/j.issn.1005-5304.2017.03.033 中图分类号：R245.9 文献标识码：A 文章编号：1005-5304(2017)03-0134-03 Research Review of Functional Mechanism of Treatment by Way of Pasting TCM on Acupoints HE Yan-ping1, XIAO Xiao-qin1, DENG Gui-ming2, OUYANG Lin-qi2, CHEN Zhen2, ZHANG Zhi-guo2 (1. Hunan University of Chinese Medicine, Changsha 410208, China; 2. First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha 410007, China) Abstract: Treatment by way of pasting TCM on acupoints has a long history and the clinical efficacy is determined. In this article, based on the concept of TCM wholism and meridian theory, the mechanism of acupoint pasting therapy was expounded from the aspects of medicine effects on local stimulation of the body, meridian conduction, medicine transdermal absorption. Combining with the research hot spots of modern medicine transdermal delivery system, metabolomics, and efficacy material, this article proposed a new study mode of systems biology of TCM. Key words: acupoint pasting therapy; mechanism of action; systems biology of TCM; review 穴位贴敷疗法最早见于《五十二病方》，是以中 机理，为今后穴位贴敷疗法的临床应用和实验研究提 医理论为基础，以整体观念和辨证论治为原则，根据 供依据。 经络学说，选取一定的腧穴，并采用适当的药物进行 1 对机体的局部刺激 贴敷，通过经络刺激与药物的作用，调理脏腑阴阳， 即相当于药物灸疗法，使局部血管扩张，促进血 疏通经络气血，从而达到预防和治疗疾病目的的一种 液循环，并通过神经反射，激发机体的调节作用。现 疗法[1-3]。