实验3：精油实验.docVIP

實驗#3:精油實驗 WARNING NOTICE: The experiments described in these materials are potentially hazardous and require a high level of safety training, special facilities and equipment, and supervision by appropriate individuals. You bear the sole responsibility, liability, and risk for the implementation of such safety procedures and measures. MIT shall have no responsibility, liability, or risk for the content or implementation of any of the material presented. Legal Notices 警告：在這些資料中所描述的實驗是有潛在危險的，而且要求有高度的安全訓練、特別的設施和裝備，且要有適當的人員監督下才能進行的。你要獨自承擔責任， 義務，而且要為履行上述的安全手續和措施負責。麻省理工學院將沒有責任，義務，或是為滿足上述材料提及到的安全措施而負責。法律說明 MASSACHUSETTS INSTITUTE OF TECHNOLOGY 麻省理工學院 Department of Chemistry 化學系 5.310 Laboratory Chemistry 5.310化學實驗 EXPERIMENT #3 實驗#3 ESSENTIAL OILS 精油1 INTRODUCTION I. 簡介 In this experiment you will be working with oils prepared from caraway seeds and spearmint leaves. Each oil has a distinct and characteristic odor, yet carvone is the major component in both oils! It is amazing that the difference in odor is attributable solely to a difference in chirality of the carvone in the two oils. Due to chirality of odor receptors in the nose the R-carvone and S-carvone fit into different receptor sites, hence different odor. Can you distinguish between the odors? 8-10% of the population cannot. Some physical data are presented below. 在這個實驗2中，你將從葛縷子種子和綠薄荷葉中提煉出油來。兩種油各自有種與眾不同的氣味，然而香芹酮是這兩種油中的主要成分！ 令人吃驚的是氣味的不同完全是由於兩種油中香芹酮手性的不同而引起的。由於鼻子中氣味感受體的手性。R-香芹酮和S-香芹酮與不同的感受體位置結合，因而感受到不同的氣味。你能夠區別這兩種氣味嗎？ 8-10%的人不能3。以下顯示了一些物理數據4。 (S)-(+)-Carvone (R)-(-)-Carvone (S)-(+)-香芹酮 (R)-(-)-香芹酮 FW = 150.22; bp 98-100/10 mm Fw=150.22; bp 227-230 oC 分子量=150.22；沸點98-100/10 mm 分子量=150.22；沸點227-230 oC nD20 = 1.4970; d=0.9608 g/mL nD20 = 1.4990; d=0.9593 g/mL [α]D20=+61.7 o (neat 96%) [α]D20=-62.5 o (neat 98%) [α]D20=+61.7 o (純度96%) [α]D20=-62.5 o (純度98%) major