Mannitol improves absorption and retention of calcium and magnesium in growing rats》.pdfVIP

Nutrition 29 (2013) 325–331 Contents lists available at ScienceDirect Nutrition journal homepage: Basic nutritional investigation Mannitol improves absorption and retention of calcium and magnesium in growing rats Jin Xiao M.D., Xiao Li Ph.D., Xiao Min M.D., Ei Sakaguchi Ph.D. * Division of Bioscience, Faculty of Agriculture, Okayama University, Okayama, Japan a r t i c l e i n f o a b s t r a c t Article history: Objective: Resistant sugars, which have several desirable properties, are often used in food Received 29 December 2011 production and the pharmaceutical industry. We evaluated the effects of mannitol on the Accepted 30 June 2012 absorption and retention of calcium (Ca) and magnesium (Mg) in growing rats. Methods: In experiment 1, 4-wk-old growing male Wistar rats were given a control diet (C) or Keywords: mannitol diets containing 2%, 4%, 6%, or 8% mannitol (2M, 4M, 6M, or 8M, respectively) for 28 d to Mannitol measure the absorption and retention of Ca and Mg. In the last 7 d of the feeding trial, the non- Calcium absorbable marker chromium-mordant cellulose was added to the experimental diets to estimate Magnesium Absorption Ca and Mg absorbability in the intestinal segments. In experiment 2, 9-wk-old growing male Wistar Cecum