臭氧治疗外阴阴道假丝酵母菌病的临床研究.pdfVIP

·2 3 · 臭氧治疗外 阴阴道假 丝酵母 菌病 的临床研 究 沈慧敏 杨越波 黄敏 李小毛 刘晓霞 李卉 张宇 【摘要 】 目的 评价臭氧治疗外阴阴道假丝酵母菌病 的有效性和安全性。方法 采用 随机对照、 开放设计 ，人选外阴阴道假丝酵母菌病患者 27 例 ，其 中试验组 36 例接受臭氧治疗 ，对照组 36 例接受达 克宁栓治疗 ，于治疗前 、治疗结束后第3 天观察临床症状及体征 ，并进行阴道分泌物病原学检查 。结果 治疗结束后第3 天，试验组和对照组的痊愈率分别为58 3% 和61 . 1% ，有效率分别为 38 . 3% 和 88 . 9% ， 症状平均缓解时间分别为2 . 58 d 和2. 36 d ，假丝酵母菌阴转率分别为49 . 4 % 和 01 0% 。2 组之间比较差 异均无统计学意义( P 0. 05 ) 。27 例病例 中无不 良事件与严重不 良事件发生 。结论 臭氧治疗外阴阴 道假丝酵母菌病安全 、有效。 【关键词 】 臭氧;硝酸咪康哇栓 ;外阴阴道假丝酵母菌病 A Clinical Tr ial of 0 zone 1n T e Tr eatment of Vulvovaginal Can didiasis SHEN Hui一min ，AY NC uY e一bo ， HUA NC 对in ，e公al. D印a此。ent of obste rti c and 分ncoe logy ，T e T ird 逃加1艺a名翻 刀吞胡1术al ，SU八zya t一sen Un i雌rs i- yt ，Cuanzg o “5 10630 ，C ina [Abstr act ] ojb ective To evaluate t e eiff cacy and saef ty of ozone in t e treatment of vulvovaginal can- didiasis. Met ods A randomized ，controlled ，open clinical trial including 72 cases sueff red vulvovaginal candi- diasis was conducted ‘36 cases in trila gro up were given ozone t erapy and 36 cases in contro l gro up were given miconazole nitrate suppositories. 3days aif er t e end of treatment ，Compared t e c ange of clinicla symptoms and signs ，t e result of BV blue examination between trial group and control group. Reus lts 3days atf er t e end of treatment ，t e cure ra tes were 58. 3% in trial grouP and 6 1，1% in contro l gro uP ，t e eiff cacy rates were 83. 3% in trial group and 88. 9% in control group ，t e average periods of symptom relaxing were 2. 58days in trial group and Z. 36days in control gro up . T ere were no signiif cant dieff re nces between t ese 姗o groups ( P 0. 05) . T e eradicated rates of pat ogen were 94 . 4% in tri al gro up and l 00% in contro l group . T ere were no signiif - cant dieff rences between t ese two gro ups in er