应用ICP-AES法分析不同产地滑石粉中元素构成的差异.pdfVIP

应用ICP-AES法分析不同产地滑石粉中元素构成的差异* 1 1** 1 2 2 张萍 ，肖新月 ，魏锋 ，石上梅 ，钱忠直 （1 中国食品药品检定研究院 北京 100050 2 国家药典委员会 北京 100061） 摘要 目的：建立了电感耦合等离子体发射光谱（ICP-AES）法测定不同产地滑石粉中 10 种无机元素分析方法，分析不同产地滑石粉中的元素组成及含量。方法：采用湿法消解前处 理，电感耦合等离子发射光谱法分析滑石粉中 10 种无机元素，用 SPSS 17.0 对数据进行聚 类分析。结果：检测了滑石粉药材中 10 种元素，其中 Mg 为主要元素，Ca, Al, Fe 为微量 元素，聚类分析结果表明，样品被分为 4 类。重金属及有害元素中 Pb, As, Hg, Cr 均有部 分样品检出，提示滑石粉的安全性应得到重视。结论：该法为滑石粉药材的有效性、安全性 评价及质量标准的修订提供了科学的参考依据。 关键词：电感耦合等离子体发射光谱；滑石粉；无机元素 ICP-AES analytical studies on inorganic elements of Mineral Chinese Medicine Talci Pulvis from different hibitats 1 1 1 2 2 ZHANG Ping , XIAO Xin-yue ,WEI Feng , SHI Shang-mei , QIAN Zhong-zhi (1 National Institutes for Food and Drug Control Beijing 100050 2 China Pharmacopoeia Committee Beijing 100061) Abstract Objective: A method was established for the determination the contents of the inorganic elements in talci pulvis from different hibitats. Method: Samples were digested with Wet digestion method and determined by inductively coupled plasma-atomic emission spectrometry (ICP-AES) method and the data of hierarchical cluster analysis were analyzed with the SPSS 17.0 software. Result: 10 inorganic element were determined. The inorganic element Mg was the major element and the elements Ca, Al, Fe were the trace elements in talci pulvis. The result of hierarchical cluster analysis showed that the 47 samples were distributed into four categories. The content of Pb, As, Hg, Cr were checked in parts of samples, it implied that we should pay attention to the safety of talci pulvis. Conclusion: It provided a scientific reference for the quality analysis, safety assessment and quality standard es