87例百日咳住院患儿的临床特征分析.docxVIP

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87例百日咳住院患儿的临床特征分析.docx

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87例百日咳住院患儿的临床特征分析

李欣宇杨晓庆吴谨准董鸿捌陈云娥郑雅玲

[关键词]?百日咳；临床特征；儿童

[中图分类号]?R725.1??????[文献标识码]?A????[DOI]?10.3969/j.issn.1673-9701.2024.04.009

Analysis?of?clinical?features?of?87?hospitalized?children?with?pertussis

LI?Xinyu，?YANG?Xiaoqing，?WU?Jinzhun，?DONG?Hongba，?CHEN?Yune，?ZHENG?Yaling

Department?of?Paediatrics，?Women?and?Childrens?Hospital?Affiliated?to?Xiamen?University，?Xiamen?361003，?Fujian，?China

[Abstract]?Objective?To?investigate?the?clinical?features?of?hospitalized?children?with?pertussis.?Methods?The?clinical?data?of?87?hospitalized?children?with?pertussis?admitted?to?Women?and?Childrens?Hospital?Affiliated?to?Xiamen?University?from?January?2019?to?December?2022?were?retrospectively?analyzed.?According?to?the?age?of?the?children，?they?were?divided?into?group?A?（≤3?months?of?age，?35?cases），?group?B?（4-12?months?of?age，?36?cases）?and?group?C?（12?months?of?age，?16?cases）.?The?clinical?features?of?children?at?different?ages?were?compared.?Results?The?majority?of?children?with?pertussis?were?1?year?old?（81.61%），?and?August?was?the?month?of?high?incidence.?Spastic?cough?（72.41%）?was?the?main?clinical?manifestation.?Other?manifestations?included?redness?or?cyanosis，?vomiting?after?coughing，?crow?echo，?etc.?There?were?statistically?significant?differences?in?the?incidence?of?spastic?cough，?redness?or?cyanosis?and?the?contact?history?of?patients?with?chronic?cough?among?three?groups?（P0.05）.?There?were?significant?differences?in?the?incidence?of?pneumonia?and?the?average?length?of?hospital?stay?among?three?groups?（P0.05）.?There?was?significant?difference?in?C-reactive?protein?level?among?three?groups?（P0.05）.?Among?87?children?with?pertussis，?37?cases?（42.53%）?were?infected?with?other?pathogens，?among?which?virus?infection?was?the?most?common.?The?treatment?is?effective?with?macrolides?and?compound?sulfamethoxazole.?Conclusion?Pertussis?is?more?common?in?infants?under?1?year?of?age，?and?the?incidence?is?high?in?August?.?Chronic?cough?patients?with?close?contact?ma