低水平铅暴露对雄性幼兔睾丸组织和内分泌激素影响的研究（职称论文资料）.docVIP

低水平铅暴露对雄性幼兔睾丸组织和内分泌激素影响的研究（职称论文资料） 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：低水平铅暴露对雄性幼兔睾丸组织和内分泌激素影响的研究 1 1 材料和方法 3 2 结果 7 3 讨论 8 文2：乙酰甲胺磷对雄性大鼠睾丸组织抗氧化能力的影响 11 1 材料和方法 12 2 结果 13 3 讨论 14 参考文摘引言： 15 原创性声明（模板） 17 文章致谢（模板） 17 正文 低水平铅暴露对雄性幼兔睾丸组织和内分泌激素影响的研究（职称论文资料） 文1：低水平铅暴露对雄性幼兔睾丸组织和内分泌激素影响的研究 The Effect of Low-Level Lead Exposure on the Testicle Tissue and Hormone of Male Rabbits in Juvenile Stage YU Gao-yan1，YAN Chong-huai1*，YU Xiao-gang1，ZUO Yong2，YU Xiao-dan1，XU Jian1，ZHANG Yan-ping1，ZOU Xiang-yu1（ XinHua Hospital Affiliated to School of Medicine，Shanghai Jiao Tong Univeity，Shanghai Ititute for Pediatric Research，Shanghai Key Laboratory of Childrens Environmental Health，Shanghai 200092，China；. of Cell Biology，School of Medicine，Shanghai Jiao Tong Univeity，Shanghai 200025，China） Abstract：［Objective］ To explore the effect of low-level lead exposure on the testicle tissue and hormone of male rabbits in juvenile stage. ［Methods］ Sixteen 45-day-old male New Zealand rabbits were randomly divided into control group and lead-exposed group with 8 in each group. Rabbits in the lead-exposed group were treated with 5 mg/kg?day lead acetate in their forage for 6 weeks to establish low-level lead exposure animal model. The blood lead levels and the lead concentratio in testicle were determined by atomic absorption spectrometer（AAS）and inductively coupled plasma-mass spectrometry（ICP-MS）respectively. Histopathology and ultra-microstructure in testicle tissue were observed under light microscope and electron microscope. The levels of testosterone（T），luteinizing hormone（LH）and follicular stimulating hormone（FSH）in serum were analyzed by enzyme linked immunosorbent assay（ELISA）. ［Results］ Compared with the control group，there were significant increase in blood lead levels and lead concentratio in testicle in the lead-exposed group（for blood lead levels：t = ，P ； for lead concentratio in testicle：t = ，P ），significant decrease in testicle wet weight（t =