第八章合成生物学2-11-7.ppt

* 无法创造的东西，我无法理解——只有通过创造才能理解。不能理解的东西，我无法创造。 What I cannot create I do not understand. ——美国物理学家理查德·费曼 * * hierarchical adjective of the nature of a hierarchy; arranged in order of rank 等级制度的，分等级的 * * * * * * * * * * * * * * * * * * * Early hopes for a code to simply map amino-acid residues to DNA bases have not materialized * * * * Standards for constructions. Functionally connect things in a standard way. Physical connections (screw thread, Knight’s standard assembly scheme) .Functional connections. Characterization of performance Polymerase Per Second = PoPS! * For example, there are very few programmers that could either design an operating system or build their own circuit board * * * /law/conferences/ip/Rai.pdf Viral licensing was popularized by Richard Stallman at MIT. There is concern that much good code that was freely given to the open source community was being adapted by a software monopolist who would customize the code to run on the monopolists operating systems. The monopolist would copyright the adaptation and then reap substantial profits by requiring use of the adaptation as part of the OS package. Viral licensing would require the monopolist to make any adaptations freely available to the public. * /wiki/Synthetic_Society/Ownership,_sharing_and_innovation * /wiki/Synthetic_Society/Ownership,_sharing_and_innovation * /wiki/Synthetic_Society/Ownership,_sharing_and_innovation * However, due to the previous effort that has been invested in zinc finger proteins, it would require a considerable investment of time and money to find a substitute adaptation. Additionally, zinc finger proteins are widely acknowledged to represent the most elegant adaptation to the general problem of having proteins that bind to every possible DNA sequence and thus circumventing such a patent might involve having to pursue a second-rate adaptation. * Ziconitide – pain relief, analgesic * * * /choiceisyours/choiceisyours.2006.05.30.htm * /choiceisyours/choiceisyours.2006