经皮椎间孔镜下微创手术联合神经生长因子灌注治疗腰椎间盘突出症的临床研究.docVIP

经皮椎间孔镜下微创手术联合神经生长因子灌注治疗腰椎间盘突出症的临床研究 　　DOI：10.16662/j.cnki.1674-0742.2017.07.073 　　[摘要] 目的 探讨腰椎间盘突出症采用经皮椎间孔镜下微创手术联合神经生长因子灌注治疗的疗效。方法 方便选取86例腰椎间盘突出症患者，均为2015年3月―2016年3月期间该院收治的住院患者，随机分为对照组（经皮椎间孔镜下微创手术，n=43）与观察组（经皮椎间孔镜下微创手术+神经生长因子灌注治疗，n=43），观察两组治疗疗效及相关指标情况。 结果 观察组患者较对照组临床有效率显著要佳（P0.05），两组治疗后主要肌群肌电图均较治疗前有所改善，而治疗后，观察组腓肠肌时限、胫前肌时限均显著高于对照组（P0.05）。结论 腰椎间盘突出症采用经皮椎间孔镜下微创手术联合神经生长因子灌注治疗，疗效显著，可显著改善神经功能及疼痛症状，具有推广价值。 　　[关键词] 神经生长因子；腰椎间盘突出症；微创手术 　　[中图分类号] R687 [文献标识码] A [文章编号] 1674-0742（2017）03（a）-0073-03 　　Clinical Research on Transforaminal Endoscopic Minimally Invasive Surgery and Nerve Growth Factor in Perfusion Treatment of Prolapse of Lumbar Intervertebral Disc 　　LI Guo-jun， WEI Yu-feng， WANG Bing， SU Jiang-yuan， LIAN Yun 　　Department of Spine Surgery， Baiyin First People’s Hospital， Baiyin， Gansu Province， 730900 China 　　[Abstract] Objective To discuss the curative effect of transforaminal endoscopic minimally invasive surgery and nerve growth factor in perfusion treatment of prolapse of lumbar intervertebral disc. Methods 86 cases of patients with prolapse of lumbar intervertebral disc admitted and treated in our hospital from March 2015 to March 2016 were convenient selected and randomly divided into two groups with 43 cases in each， the control group were treated with transforaminal endoscopic minimally invasive surgery， while the observation group were treated with transforaminal endoscopic minimally invasive surgery and nerve growth factor perfusion， and the curative effect related indexes of the two groups were observed. Results The clinical effective rate in the observation group was obviously better than that in the control group（P0.05）， after treatment， the chief muscle group picture was improved compared with that before treatment， after treatment， the musculi gastrocnemius time limit and musculi hippicus time limit in the observation group were obviously higher than those in the control group（P0.05）. Conclusion The curative effect of transforaminal endoscopi