经皮椎体成形术与保守治疗骨质疏松致椎体压缩性骨折的随机对照研究.docVIP

经皮椎体成形术与保守治疗骨质疏松致椎体压缩性骨折的随机对照研究 　　[摘要] 目的 对比经皮椎体成形术（PVP）与保守治疗骨质疏松致椎体压缩性骨折的疗效差异。 方法 选取我院2009年7月～2014年7月收治的72例骨质疏松性椎体压缩性骨折患者作为研究对象，将所选患者随机分为研究组和对照组，研究组采用PVP术治疗，对照组采用卧床休息、药物等保守治疗，使用视觉模拟疼痛评分（VAS）评价疼痛情况，Oswestry功能障碍指数问卷表（ODI）评价肢体、行为功能障碍，综合比较两组患者手术前后椎体前缘高度、后凸Cobb角改善情况、VAS、ODI评分情况及椎体骨折再发风险的差异。 结果 手术后研究组患者椎体前缘高度、后凸Cobb角改善情况优于对照组（P0.05）。 结论 经皮椎体成形术治疗骨质疏松性椎体压缩性骨折效果确切，可有效缓解术后疼痛，改善肢体功能，不增加术后再发椎体骨折的风险，优于保守治疗，值得临床推广使用。 　　[关键词] 经皮椎体成形术；保守；骨质疏松；椎体压缩性骨折 　　[中图分类号] R683.2 [文献标识码] B [文章编号] 2095-0616（2015）20-112-03 　　A randomized controlled study of percutaneous vertebroplasty and conservative for osteoporotic vertebral compression fractures 　　LIN Weipeng YE Jin ZOU Zhongbing WU Feng WANG Huaguo OU Rongtong 　　Peoples Hospital of Yunfu City in Guangdong Province， Yunfu 527300， China 　　[Abstract] Objective To compare the effects of PVP and conservative for osteoporotic vertebral compression fractures. Methods 72 cases of osteoporotic vertebral compression fractures in our hospital were randomly divided into research group and control group， each were 36cases. Research group were treated with PVP， while control group were treated with conservative treatment. The pain was measured by visual analog pain scale （VAS） score， while limb and behavioral dysfunction was measured by oswestry disability index questionnaire （ODI）.The vertebroplasty vertebral height， Cobbs angle， VAS and ODI scores before and after surgery and risk of re-fracture of two groups were compared. Results After surgery， the ertebroplasty vertebral height and Cobbs angle of research group were better than control group （P0.05）. Conclusion PVP for osteoporotic vertebral compression fractures has exact effects. It can effectively relieve pain and improve physical function， does not increase the risk of re-fracture. Its better than conservative treatment. Its worthy of clinical widely used. 　　[Key words] Percutaneous vertebroplasty； Conservative； Osteoporosis； Vertebral compression fractures 　　骨质疏松是以单位体积内骨组织量减少为特点的代谢性骨