球囊预扩张对冠状动脉介入治疗术后心肌微损伤影响及机制-influence and mechanism of balloon pre-expansion on myocardial micro-damage after percutaneous coronary intervention.docxVIP

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球囊预扩张对冠状动脉介入治疗术后心肌微损伤影响及机制-influence and mechanism of balloon pre-expansion on myocardial micro-damage after percutaneous coronary intervention.docx

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球囊预扩张对冠状动脉介入治疗术后心肌微损伤影响及机制-influence and mechanism of balloon pre-expansion on myocardial micro-damage after percutaneous coronary intervention

Ab Abstract 学位学位论文独创性声明 PAGE PAGE V ABSTRACT Objective ： After coronary artery interventional therapy cardiac injury is a hot topic at present, because of myocardial micro damage can cause long-term prognosis, attracted widespread attention. Balloon dilation is an important process of coronary artery interventional therapy, this study through the randomized method, respectively, in patients underwent a 2.0mm balloon angioplasty / stenting and 2.5mm balloon angioplasty / stenting, a comparative study of these two effects of different diameter balloon on cardiac muscle after operation of micro damage, so as to help select the appropriate balloon to reduce myocardial damage, reduce inflammation, protecting myocardial cells, protect the cardiac function, reduce the times of hospitalization, and improve the prognosis of patients, reduce the adverse cardiovascular events. Methods ： Selected in 2013 September to 2014 August in our hospital in two hospital and underwent elective PCI surgery in patients with coronary artery disease (including stable angina, unstable angina and myocardial infarction) in 108 cases, 102 cases via the right radial artery approach, 6 cases via right femoral artery, surgical approach as the balloon dilatation and stenting, stenting for drug eluting stents. Methods randomly selected were divided into the 2.0mm balloon angioplasty / stenting and balloon dilation group 2.5mm / stenting group, in which 2.0mm / stenting group 56 cases, 2.5mm balloon angioplasty / stenting group 52 cases. The two groups according to lesion size, lesion length, the degree of coronary stenosis in vascular lesions at the line of balloon dilation in the target vessel lesion disposal into the bracket, the successful release completely cover the target vessel lesion. All patients in the preoperative PCI at 6 am in the morning fasting venous blood, to complete the routine examination such as blood routine, liver and kidney function, blood glucose, blood lipid, blood coa