(精选)癌症 (Cancer)教学课件.pptVIP

* * * * * * * * * * * * * * * * * THE ANATOMY OF AN ABSTRACT Conclusions, not titles Goals Population Samples THE ANATOMY OF AN ABSTRACT Statistics P Values, anything less than .05 is significant THE ANATOMY OF AN ABSTRACT Statistics P Values, anything less than .05 is significant Hazard Ratios HR=1.23, 95% CI, 1.05-1.10 THE ANATOMY OF AN ABSTRACT FOLLOW THE NEWS Subscribe to Newswise Check Eurekalert FOLLOW THE NEWS Subscribe to Newswise Check Eurekalert Find a PR Person you trust KEEP IN TOUCH Jeremy Moore Senior Manager, Science Communications Office: 267-646-0557 Cell: 609-519-0212 jeremy.moore@ THANK YOU * * * * * * * * * * * * * * * * * * * * * * * * Cancer: The Scientific Questions Diagnosis Screening Screening Questions surrounding PSA, Mammography, Colonoscopy Sensitivity vs. Specificity Sensitivity Correctly Identifying Who Is Sick Specificity Correctly Identifying Who Is Not Sick MicroRNA “The discovery of MicroRNA can be equated with the idea that we’ve known for years that cars existed and only recently discovered they have a transmission. It’s that fundamental.” Philip Sharp, Ph.D., Nobel Laureate from M.I.T. MicroRNA News from Annual Meeting 2010 miR-21 and miR-106a are associated with an overall poor prognosis and that overexpressions of miR-181b and miR-203 are associated with poor outcomes in blacks for colorectal cancer MicroRNA-31 (miR-31) repressed specific tumor suppressors and, therefore, may be a novel pharmacologic target for lung cancer therapy and chemoprevention. MicroRNA News from Annual Meeting 2010 High levels of miR-21 were significantly correlated with poor response to Herceptin. DNA Methylation Levels Cancer: The Scientific Questions Diagnosis Screening Personalized Medicine Personalized Medicine Cancer: The Scientific Questions Diagnosis Screening Personalized Medicine Prevention Prevention “At least half of all cancer deaths are preventable by what we already know about healthy eating, exercise, maintaining appropr