甲状腺微小乳头状癌的临床病理特点及颈部淋巴结转移相关因素分析.docVIP

精品论文 参考文献 甲状腺微小乳头状癌的临床病理特点及颈部淋巴结转移相关因素分析 张云鹤1 王春2 冉静1 孙振柱2（通讯作者） 　　（1石河子大学医学院 新疆 石河子 832000） 　　（2新疆维吾尔自治区人民医院病理科 新疆 乌鲁木齐 830001） 　　【摘要】 目的：探讨甲状腺微小乳头状癌临床病理特征及其与颈部淋巴结转移的关系。方法：回顾2008年4月至2015年9月间我院收治的205例确诊为PTMC患者的病例资料，分析临床病理特点并复习相关文献。结果：205例PTMC患者中颈部淋巴结转移率20.0%，年龄ge;45岁、汉族、肿瘤最大径ge;0.5cm及肿瘤多发病灶与PTMC淋巴结转移有关，年龄ge;45岁、汉族、肿瘤多发病灶是其独立的危险因素。结论：对于存在年龄ge;45岁、汉族、肿瘤多灶性等淋巴结转移危险因素的患者，临床医生应采取不同的治疗策略和手术计划，以提高患者生存质量。 　　【关键词】 甲状腺微小乳头状癌；临床病理特征；淋巴结转移 　　【中图分类号】R736.1 【文献标识码】A 【文章编号】2095-1752（2016）21-0243-03 　　The clinical pathological features of papillary thyroid microcarcinoma and cervical lymph node metastasis related factors analysis 　　Zhang Yunhe1, Wang Chun2, Ran Jing1, Sun Zhenzhu2.1Shihezi University,Shihezi,832000,China; 2Department of pathology,Peoplersquo;s Hospital of XinJiang Uygur Autonomous Region,Urumqi,830001,China 　　【Abstract】Objective To explore the papillary thyroid microcarcinoma(PTMC) clinical pathological features and its relationship with cervical lymph node metastasis. Methods We analyzed the clinicopathological features of patients with PTMC . A total of 205 patients with PTMC were enrolled at our hospital between April 2008 and September 2015 and related literatures were reviewed. Results Of them,cervical lymph node metastasis were present in 41 (20%) patients.patients who were 45 years old or older, the han nationality, tumor multiple lesions were the independent risk factors. Conclusion for whose age was 45 years old or older, the han nationality, multifocal tumor , clinical doctors should adopt different treatment strategy and operation plan, in order to improve the patients quality of life. 　　【Key words】Papillary thyroid microcarcinoma; Clinical pathological features; Lymph node metastasis 　　甲状腺乳头状癌（papillary thyroid carcinoma, PTC）是最常见的内分泌恶性肿瘤[1]，约占甲状腺癌的80%[2]。此外，甲状腺微小乳头状癌（papillary thyroid microcarcinoma, PTMC）约占甲状腺癌的36%-60%[3]。PTMC被定义为甲状腺乳头状癌测量最大直径le;1.0cm[4]，据一项长达60年的随访研究提示，PTMC的发病率由最初10 年的19% 上升为最近10