瑞舒伐他汀与阿托伐他汀治疗冠心病的临床疗效.docVIP

精品论文 参考文献 瑞舒伐他汀与阿托伐他汀治疗冠心病的临床疗效 河北大学附属医院 河北 保定071000 [摘要]目的：比较瑞舒伐他汀与阿托伐他汀治疗冠心病的效果。方法：选择2014年5月至2015年6月来我院进行治疗的冠心病患者84名，按照治疗药物的不同，将患者随机分为两组，实验组（采用瑞舒伐他汀治疗）和对照组（采用阿托伐他汀治疗），每组各42名。1个月后，比较两组患者的治疗效果。结果：两组患者较治疗前血清总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-C）及三酰甘油（TG）明显降低，高密度脂蛋白胆固醇（HDL-C）水平明显升高,且实验组患者的血脂改善情况明显好于对照组，治疗效果优于对照组，且差异明显，具有统计学意义（Plt;0.05）。结论：瑞舒伐他汀与阿托伐他汀两种药物都可以明显改善冠心病患者的血脂水平，改善患者心功能，但瑞舒伐他汀的治疗效果更明显，适合在临床进行广泛应用。 关键词:瑞舒伐他汀；阿托伐他汀；冠心病；治疗 【中图分类号】R815.2【文献标识码】A【文章编号】1001-5213(2016)09-0016-01 [abstract] objective: to compare rui shu laval statin with atorvastatin effect for the treatment of coronary heart disease (CHD). Methods: in May 2014 to June 2015 in our hospital for treatment of 84 patients with coronary heart disease, according to the different treatment, the patients were randomly divided into two groups: experimental group (in shu cut statin therapy) and control group (with atorvastatin therapy), each group of 42. After one month, compare the treatment effect of two groups of patients. Results: two groups of patients before the treatment serum total cholesterol (TC), low-density lipoprotein cholesterol (LDL - C) and three acyl glycerol significantly lower (TG), high-density lipoprotein cholesterol (HDL - C) level increased significantly, and the experimental group of patients with blood lipid to improve the situation is much better than the control group, the treatment effect is better than the control group, and significant difference, statistically significant (P lt; 0.05). Conclusion: rui shu laval statin with atorvastatin two drugs can significantly improve lipid levels in patients with coronary heart disease, improves cardiac function in patients, but cutting statin treatment effect is more obvious, the shu is suitable for extensive application in clinical. Keywords: shu cut statins. Atorvastatin; Coronary heart disease (CHD). treatment 冠心病是由于体内脂质代谢异常，导致动脉壁上附着由异常血脂形成的粥样斑块，使血管缩窄甚至堵塞的一种动脉粥样硬化病变性心脏病[1-2]。冠心病与体内高血脂状态有密切关系。有研究表明他汀类药物治疗可以明显改善患者的血脂水平，延缓粥样斑块的形成速度，具有保护神经及