欣普贝生在足月妊娠胎膜早破中的应用.docVIP

精品论文 参考文献 欣普贝生在足月妊娠胎膜早破中的应用 浦筱雯 祝佳 肖春（通讯作者） 　　上海市长宁区妇幼保健院产科 200051 　　【摘 要】目的 探讨欣普贝生用于足月妊娠胎膜早破促宫颈成熟及引产的有效性和安全性。方法 随机选择我院2010年12月-2012年12月足月妊娠宫颈Bishop评分le;6分、无阴道分娩的禁忌症、无应用前列腺素引产禁忌症的单胎初产妇110例，分为破膜早破及未破膜欣普贝生组。观察比较两组产妇在给药前后宫颈Bishop评分及给药后临产时间、总产程、分娩方式、羊水污染、产后出血量及新生儿情况等。结果 使用欣普贝生的自然破膜组与未破膜组在提高宫颈评分、阴道分娩率、缩短临产时间及总产程等方面无显著差异（Pgt;0.05）。在新生儿情况、羊水污染及产后出血量等方面两组亦差异不明显（Pgt;0.05）。结论 欣普贝生可促进足月妊娠胎膜早破孕妇的宫颈成熟，提高引产成功率，具有安全性与有效性。 　　【关键词】欣普贝生；胎膜早破；宫颈成熟 　　The Analysis of Propess for Promoting Cervical Mature and Induction of Labor in Full-time Pregnancy. 　　【Abstract】Objective To investigate the efficiency and safety of Propess for Promoting Cervical Mature and Induction of Labor in Full-time Pregnancy.Methods One hundred and sixty-nine pregnant women in our hospital，whose Bishop score le;6 points and without any contraindications about vaginal delivery，prostaglandin and oxytocin in induction of labor，were randomly selected and divided into the Oxytocin group without rupture of the membrane，the Propess group without rupture of the membrane and the Propess group with natural rupture of the membrane.The Bishop score before and after administration，and the time to labor starting，time of total stage of labor，modes of delivery，neonatal，amniotic fluid contamination and maternal postpartum hemorrhage amount were observed and compared among the three groups．Results Compared to the Oxytocin group，the Bishop score and vaginal delivery rate improved obviously，the time to labor starting and time of total stage of labor shortened significantly（Plt;0.01）.Moreover，there was not significantly difference between the oxytocin group and the Propess group in neonatal，amniotic fluid contamination and maternal postpartum hemorrhage amount（Pgt;0.05）.Furthermore，there was also not significantly difference between the Propess group without rupture of the membrane and the Propess group with natural rupture of the membrane in promoting cervical mature，improving vaginal delivery rate and shortening the time to lab