急诊联合检测CK-MB、cTnI、Myo 及NT-proBNP在急性冠脉综合症中应用价值.docVIP

精品论文 参考文献 急诊联合检测CK-MB、cTnI、Myo 及NT-proBNP在急性冠脉综合症中应用价值 罗海1.2 张梅1.2（通讯作者） 　　（1天津医科大学 300070；2天津武警后勤学院附属医院 300162） 　　【摘要】目的 探讨血清CK-MB、cTnI、Myo及NT-proBNP联合检测在急性冠脉综合症中临床应用价值。方法 测定不稳定型心绞痛（UAP组）86例、非ST型抬高型心肌梗死（NSTEMI组）40例、ST抬高型心肌梗死（STEMI组）75例与同期健康体检人员40例作为对照组。所有入选对象均检测血清CK-MB、cTnI、Myo及NT-proBNP并进行分析。结果 血清CK-MB、cTnI、Myo及NT-proBNP的水平随冠状动脉疾病病情的逐渐加重而递增，血清CK-MB、MYO及NT-proBNP水平与cTnI水平呈正相关，STEMI组血清标志物水平明显高于其他三组，具有显著性相关（Plt;0.01），NSTEACS者与对照组亦具有显著差异性（Plt;0.01）。结论 血清CK-MB、cTnI、Myo及NT-proBNP联合检测在急性冠脉综合症的诊断，病情严重程度再梗死、预后判断及随诊等方面具有重要的临床意义。 　　【关键词】 冠心病 急性冠脉综合征 血清CK-MB cTnI Myo NT-proBNP 　　【中图分类号】R446 【文献标识码】A 【文章编号】2095-1752（2013）33-0022-02 　　The application value in emergency of combined detection of CK-MB,cTnI,Myo and NT-proBNP in acute coronary syndrome 　　luo Hai 1,2 zhang Mei 1,2 （Author for correspondence） (1.Tianjin Medical University 300070， China；2.Department of Emergency, Affiliated Hospital of Logistic University Chinese Peoplersquo;s Armed Police Forces,Tianjin 300162,China) 　　【Abstract】Objective Discussion of the clinical application value in emergency of combined detection of CK-MB,cTnI,Myo and NT-proBNP in acute coronary syndrome.Methods Determination of 75 patients with ST elevation myocardial infarction (STEMI group),40 patients with non ST elevation myocardial infarction (NSTEMI group),86 patients with unstable angina pectoris (UAP group) and the control group with 40 cases is the same time of health physical examination personnel.All of the participants have to detect serum CK-MB,cTnI,Myo and NT-proBNP,and you must analyze the results. Results The results showed that the CK-MB,cTnI,Myo and NT-proBNP levels increased in patients with coronary artery disease gradually aggravated. Serum CK-MB,MYO and NT-proBNP level are positively correlated with cTnI level.The serum marker levels in group of STEMI are significantly higher than the other three groups, and the difference is significant (Plt;0.01),t