保妇康栓治疗宫颈上皮内瘤变1级40例临床分析.docVIP

精品论文 参考文献 保妇康栓治疗宫颈上皮内瘤变1级40例临床分析 徐秀华 李旭 张晓俊（江苏省宿迁市人民医院妇产科 223800） 【中图分类号】R737.33【文献标识码】A【文章编号】1672-5085（2011）40-0017-02 【摘要】目的 观察中药保妇康栓治疗伴有人乳头瘤病毒(HPV) 感染的宫颈上皮内瘤变(CIN)1级的临床疗效。方法 81例伴HPV感染的CIN1级患者随机分为治疗组40例和对照组41例。治疗组采用保护康栓阴道内置药3个月后，停药3天后复查；对照组不使用任何药物；两组均于3个月后复查杂交捕获二代（HCII）、液基细胞学（LCT）、阴道镜下活检（LCT异常者）。结果 3个月后HCII显示治疗组HPV感染转阴30例，转阴率75%，对照组转阴19例，转阴率46.3%，两组比较有显著性差异(Plt;0.01); LCT或阴道镜下活检显示治疗组CIN1级转为慢性炎症24例（60%），对照组转为慢性炎症者14例（34.1%），两组比较有显著性差异(Plt;0. 01)。结论 保妇康栓治疗伴有人乳头瘤病毒感染的宫颈上皮内瘤变疗效满意,是较为理想的方法。 【关键词】宫颈上皮内瘤变 人乳头瘤病毒 保妇康栓 Paul Fukang suppository in the treatment of cervical intraepithelial neoplasia Ⅰ40 patients 【Abstract】 Objective : Observe the effects of Paul Fukang suppository in the treatment of people with papillomavirus (HPV) infection in cervical intraepithelial neoplasia (CIN) Ⅰ level of clinical efficacy.Method:Method : 81 cases of CIN1 with HPV infection level were randomly divided into treatment group of 40 patients and a control group of 41 patients. Treatment group were built to protect health medicine vaginal suppository after 3 months, 3 days after withdrawal review; Control group did not use any drugs; Both groups at 3 months after the review Hybrid Capture II (HCII), liquid-based cytology (LCT), colposcopy and biopsy (LCT abnormalities). Result: months after the HCII negative HPV infection showed that the treatment group, 30 cases, Negative rate of 75%, Negative control group, 19 cases, Negative rate of 46.3%, Two groups had significant difference (Plt;0.01); LCT or colposcopy and biopsy showed that the treatment group CIN1-level chronic inflammation in 24 patients (60%), To chronic inflammation in the control group, 14 patients (34.1%), Two groups had significant difference (Plt;0.01). Conclusion: Paul Fukang suppository in the treatment of human papillomavirus infection with cervical intraepithelial neoplasia with satisfactory outcome, it is the ideal method. 【Key words】Cervical intraepithelial neoplasia Human papillomavirus Paul Fukang bolt