acei与β－受体阻滞剂联合应用治疗慢性心力衰竭的治疗效果及远期随访观察.docVIP

精品论文 参考文献 ACEI与β－受体阻滞剂联合应用治疗慢性心力衰竭的治疗效果及远期随访观察 湖南航天医院 心血管内科 410205 【摘 要】目的：观察分析联合应用ACEI与beta;－受体阻滞剂对治疗慢性心力衰竭的临床治疗效果及远期疗效观察。方法：选取2013年2月-2015年2月在我院心血管科接受治疗的68例慢性心力衰竭患者，将其随机分为治疗组与对照组，所有患者均予以洋地黄药物、利尿药物治疗，治疗组在行强心、利尿治疗的基础上，联合应用血管紧张素转换酶抑制剂（ACEI）依那普利片与beta;－受体阻滞剂酒石酸美托洛尔片。在治疗前、治疗后半个月、3个月、6个月时比较两组患者的各项心功能指标。结果：治疗半个月后，治疗组与对照组患者心功能指标均较治疗前改善（P＜0.05），治疗组治疗3个月、6个月后，与治疗半个月后对比，心功能明显改善，P＜0.05，差异有统计学意义，对照组进一步治疗后，与治疗半个月后对比，心功能无进一步改善（P＞0.05）。结论：慢性心力衰竭患者在治疗过程中，加用ACEI与beta;－受体阻滞剂，能显著改善患者的心功能指标及心衰症状，获得良好的远期疗效，值得临床上推广使用。 【关键词】ACEI；beta;－受体阻滞剂；慢性心力衰竭；远期疗效 【Abstract】Objective：Analyze the combined use of ACEI with beta blockers in the treatment of chronic heart failure clinical treatment effect and the long-term curative effect observation.Method：Selection in February 2013 - February 2015 in our hospital cardiovascular division for treatment of 68 cases of patients with chronic heart failure，which were randomly divided into treatment group and control group，all patients be drug digitalis，diuretic drug treatment，treatment group was treated in strong heart，diuresis，on the basis of combined use of angiotensin converting enzyme inhibitors（ACEI）enalaprilat piece and beta blockers tartrate metoprolol.In half a month before and after treatment，3 months，6 months to compare the cardiac function indexes of two groups of patients.Results：Half a month after treatment，the treatment group and control group in patients with cardiac function indexes to improve before the treatment（P lt; 0.05），the treatment group after treatment for 3 months，6 months，compared with half a month after treatment，cardiac function improved significantly，P lt; 0.05，the difference was statistically significant，the control group after further treatment，compared with half a month after treatment，no further improve cardiac function（P gt; 0.05）.Conclusion：In the process of treatment，patients with chronic heart failure with ACEI and beta blockers，can significantly improve cardiac function indexes and heart fai