59例子宫腺肌病患者放置左炔诺孕酮宫内缓释系统疗效分析.docVIP

精品论文 参考文献 59例子宫腺肌病患者放置左炔诺孕酮宫内缓释系统疗效分析 龚明霞 吴俊妍 杨季 　　(江苏省张家港市妇幼保健所 江苏 张家港 215600) 　　【摘要】 目的：探讨子宫腺肌病患者放置左炔诺孕酮宫内缓释系统(LNG-IUS)的临床效果。方法：随访2010年5月—2013年5月我所门诊放置左炔诺孕酮宫内缓释系统（曼月乐）的子宫腺肌病患者59例，观察放置前和放置后1、3、6、12个月的痛经程度、月经量及不良反应。结果：放置曼月乐后患者痛经程度明显减轻,放置后与放置前比较差异有统计学意义（P＜0.01），放置后各月份间比较差异有统计学意义（P＜0.01）；放置后患者的月经量较放置前明显减少或闭经（P＜0.01）；放置后常见不良反应为阴道点滴出血、闭经、环位下移等，但发生率较低能被患者接受。结论：左炔诺孕酮宫内缓释系统能明显缓解子宫腺肌病患者临床症状，提高患者生活质量，不良反应小，适合临床推广应用。 　　【关键词】 子宫腺肌病；曼月乐；痛经；月经量 　　【中图分类号】R71 【文献标识码】A 【文章编号】2095-1752（2015）12-0044-02 　　Efficacy Analysis of 59 Cases of levonorgestrel-releasing intrauterine system Treatment of adenomyosis 　　Gong Mingxia Wu Junyan Yang ji Maternal and Child Health Hospital of Zhang jiagang,Jiangsu,Zhangjiagang, 215600,China 　　【Abstract】Objective?To investigate the clinical efficacy of levonorgestrel-releasing intrauterine system(LNG-IUS) in the treatment of adenomyosis. Methods Fifty nine cases of adenomyosis treated with LNG-IUS( Mirena )in our hospital from May 2010 to May 2013 were followed-up, The change of dysmenorrhea and menstrual volume and adverse reaction before and after 1，3，6,12 months were observed．Results The menstrual volume is markedly decreased after treatment，with statistical significance(Plt;0.01),After treatment compared between each month,the difference had statistical significance(Plt;0.01),After treatment ,the menstrual volume was decreased significantly or amenorrhea(Plt;0.01) ;small amount of vaginal bleeding、amenorrhea and were the most common adverse reaction ,the low incidence of adverse reactions can accepted by patients.Conclusion The effect of levonorgestrel—releasing intrauterine system in adenomyosis is obvious，it can relieve the clinical symptoms、improve the quality of life，and has a low rate of adverse reactions，so it is suitable for Clinical application. 　　【Key words】Adenomyosis;Mirena;Dysmenorrhea;Menstrual volume 　　当子宫内膜腺体及间质侵入子宫肌层时，称子宫腺肌病[1]。本病多发生于30～50岁经产妇 [2]。主要症状是经量过多、进行性加重的痛经，严重影响患者生活