2型糖尿病患者真菌性泌尿系感染的真菌菌群分布及耐药性分析.docVIP

精品论文 参考文献 2型糖尿病患者真菌性泌尿系感染的真菌菌群分布及耐药性分析 山东省临沂罗庄中心医院 276017 　　【摘要】目的 分析２型糖尿病并发泌尿系感染的病原菌分布及耐药性，以给当前临床上抗菌药物的合理使用提供参考依据。方法 将病原菌用常规的方法分离开，然后运用沉渣划线法对血平板、麦康凯平板进行接种，然后放置于35℃的孵育箱中培养24ｈ，之后鉴定菌种并进行药敏试验。结果 300例标本中共分离出316株细菌，同时检出细菌和真菌两种共5例，其中革兰阴性菌共有154株，占48.73％；革兰阳性菌共有131株，占41.46％；真菌共有31株，占9.81％。316株病原菌中共有30株真菌没有做药敏试验，其余286株病原菌中大肠埃希菌对青霉素类耐药性较高，其中青霉素Ｇ的耐药性为94.03％，表皮葡萄球菌、金黄色葡萄球菌和肺炎克雷伯菌对氨苄西林耐药性最高均为100.0％，粪肠球菌对红霉素耐药性最高为100.0％。结论 2型糖尿病患者并发泌尿系感染具有较高的发病率，病原菌的种类大部分都是革兰阴性菌和革兰阴性菌，真菌感染比较多，耐药菌株也增加了，临床上在选择抗菌药物时应该根据病原菌的种类和药敏结果科学的选择药物，以保证抗菌效果。 　　【关键词】2型糖尿病；泌尿系统感染；病原菌分布和耐药性 　　[Abstract] Objective： To analyze the distribution and drug resistance of pathogenic bacteria in type 2 diabetes complicated with urinary tract infection, so as to provide reference for the rational use of antibiotics in clinical practice. Methods： pathogenic bacterium by conventional method separated, then using sediment marking method on blood agar, MacConkey plates were inoculated, and then placed in 35 DEG C to brood rearing box medium for 24h. After strain identification and drug sensitive test. Results ：300 specimens CPC isolated 316 bacterial strains, detection of bacteria and fungi in two for a total of five cases, which gram negative bacteria total 154 strains, accounted for 48.73; gram positive bacteria total 131 strains, (41.46%; fungal total 31 strains, accounting for 9.81%. 316 strains of pathogenic bacteria isolated from a total of 30 strains of fungi did not do the drug sensitivity test, remaining 286 strains of pathogenic bacteria Escherichia coli to penicillins antibiotic resistance was higher, which resistance to penicillin G was 94.03%, Staphylococcus epidermidis and Staphylococcus aureus and pneumonia Klebsiella pneumoniae strains to ampicillin resistant highest were 100.0%, Enterococcus faecalis to erythromycin resistance for a maximum of 100%. Conclusion： type 2 diabetes patients complicated with urinary tract infection with a high incidence, types of pathogens are mostly gram negative bacteria and